...Guoxing Wan; Xue Sun; Fang Li; Xuanbin Wang; Chen Li; Hongliang Li; Xianjun Yu; Fengjun Cao Background/Aims: Previous studies on the effect of metformin therapy on survival of pancreatic cancer patients obtained inconsistent findings. To reevaluate the prognostic value of metformin adjuvant...

...Tingyan Shi; Pan Wang; Wenbin Tang; Rong Jiang; Sheng Yin; Di Shi; Qing Wang; Qingyi Wei; Rongyu Zang Background/Aims: Prognostic value of germline BRCA1 or BRCA2 ( gBRCA1/2 ) mutations in epithelial ovarian cancer (EOC) remains controversial, especially in the estimation of long-term survival. We...

... type mice survived, all SGLT1 deficient mice died from the infection. Conclusions: SGLT1 is required for bacterial clearance and host survival following murine Listeria infection. [email protected] 24 04 2017 23 05 2017 14 7 2017 © 2017 The Author(s). Published...

... miR-30d as a prognostic marker of survival in patients with AHF has not been explored. Methods: Patients clinically diagnosed with AHF were enrolled and followed up for 1 year. Quantitative reverse transcription polymerase chain reactions were used to determine serum miR-30d levels. The univariate...

... expression in tumor tissue and the corresponding normal tissue was detected using immunohistological staining. The correlations between Bmi-1 expression and clinicopathological characteristics and the overall survival (OS) time were analyzed. Results: The median H-scores of Bmi-1 in CC tissues...

...Ying Zhu; Chaoxiong Zhang; Changxin Gu; Qiang Li; Ning Wu Background/Aims : Non-small cell lung cancer (NSCLC) tissues overexpress USP14, which promotes tumor cell proliferation and is associated with shorter overall survival time. Methods: The expression of USP14 was assayed in many types...

...Yuliang Su; Huan Zhang; Fangxiu Xu; Jinyu Kong; Herbert Yu; Biyun Qian Background: Single nucleotide polymorphisms (SNPs) in the DNA repair genes are suspected to be related to the survival of lung cancer patients due to their possible influence on DNA repair capacity (DRC). However, the study...

... transcription factor that mediates cellular responses to hypoxia. Methods: We investigated the effect of isoflurane preconditioning on bone marrow stromal cell (BMSC) survival and function. Results: Short exposures to low isoflurane concentrations promoted in vitro survival and migration of BMSCs, whereas long...

... between serum 25(OH)D levels and prognosis of patients with hematological malignancies. The hazard ratios (HR) with 95% confidence intervals (95%CI) for overall survival (OS) or relapse-free survival (RFS) were pooled using meta-analysis. Results: Seven studies with a total of 2,643 patients...

... of survival of the subsets cultured under different conditions: with medium alone, with 10% autologous plasma, with EPO, alone or in combination with autologous monocytes. Results: Neocytes showed a viability and a survival rate lower than the other red cells when cultured in medium or with 10% plasma. EPO...

... apoptosis during prenatal life through adulthood. Our previous studies revealed high levels of the lipid hydrolase, acid ceramidase (AC), in human and mouse oocytes, follicular fluid and cumulus cells. In addition, supplementation of in vitro fertilization media with recombinant AC enhanced the survival...