... phenomenon occurs when a sandwich is formed when insulin molecule and the two antibodies come into close proximity and is proportional to the concentration of insulin. Streptozotocin (STZ), NAC, reduced and oxidized glutathione(GSH/GSSG), cumene hydroperoxide, glutathione reductase, 3-(4, 5...

...Ting Ju; Yuru Li; Xiaoran Wang; Lifeng Xiao; Li Jiang; Shanshan Zhou; Meimei Yang; Tingting Zhao; Lina Sun; Tingjiao Liu; Jinghan Lin; Yi Xu; Liming Zhang Background: Streptozotocin (STZ) has served as an agent to generate an Alzheimer's disease (AD) model in rats, while edaravone (EDA), a novel...

... with streptozotocin-induced type I diabetes were investigated using proteomic tools; non-diabetic mouse oocytes were used as controls. Immunofluorescence analysis for the spindle and mitochondria of oocytes. Results: We found that type I diabetes severely disturbed the metabolic processes of mouse oocytes. We also...

...Saritha Marella; Dilip Rajasekhar Maddirela; Kameswara Rao Badri; Malaka Venkateshwarulu Jyothi Kumar; Apparao Chippada Background: This study was aimed to evaluate the protective effects of a novel anti-hyperglycemic “Mcy protein” isolated from the fruits of Momordica cymbalaria in streptozotocin...

... and respiratory susceptibility to diesel exhaust particles (DEP) in mice with type 1 diabetes. However, the pancreatic effects of DEP in healthy and diabetic mice are unknown. Methods: Presently, we evaluated the pancreatic impact of DEP in healthy mice, and mice with streptozotocin-induced type 1 diabetes. Four...

... in cognitive functions and the level of hyperphosphorylated tau proteins in central insulin-resistant rats. Methods: An in vivo central insulin-resistant (CIR) animal model was generated through intracerebroventricular injection of streptozotocin (STZ) into insulin-resistant (IR) rats that were induced...

... (T1DM) results from autoimmune destruction of pancreatic β-cells, leading to absolute insulin deficiency in patients as well as a requirement for exogenous insulin supplementation for survival [ 6 ]. To induce experimental T1DM in animals, streptozotocin (STZ) has been widely used due to its cytotoxic...