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Keywords: Streptozotocin
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Cellular Physiology and Biochemistry (2016) 39 (6): 2320–2330.
Published Online: 07 November 2016
... with streptozotocin-induced type I diabetes were investigated using proteomic tools; non-diabetic mouse oocytes were used as controls. Immunofluorescence analysis for the spindle and mitochondria of oocytes. Results: We found that type I diabetes severely disturbed the metabolic processes of mouse oocytes. We also...
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Journal Articles
Cellular Physiology and Biochemistry (2014) 33 (2): 413–422.
Published Online: 11 February 2014
... and respiratory susceptibility to diesel exhaust particles (DEP) in mice with type 1 diabetes. However, the pancreatic effects of DEP in healthy and diabetic mice are unknown. Methods: Presently, we evaluated the pancreatic impact of DEP in healthy mice, and mice with streptozotocin-induced type 1 diabetes. Four...
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Cellular Physiology and Biochemistry (2013) 32 (5): 1417–1425.
Published Online: 28 November 2013
... in cognitive functions and the level of hyperphosphorylated tau proteins in central insulin-resistant rats. Methods: An in vivo central insulin-resistant (CIR) animal model was generated through intracerebroventricular injection of streptozotocin (STZ) into insulin-resistant (IR) rats that were induced...
Journal Articles
Cellular Physiology and Biochemistry (2013) 31 (2-3): 408–420.
Published Online: 12 March 2013
... (T1DM) results from autoimmune destruction of pancreatic β-cells, leading to absolute insulin deficiency in patients as well as a requirement for exogenous insulin supplementation for survival [ 6 ]. To induce experimental T1DM in animals, streptozotocin (STZ) has been widely used due to its cytotoxic...