... used to replace serum proteins in biofilm formation assays. A rat central venous catheter model was developed to evaluate the effect of NAC on biofilm formation in vivo . Results: NAC and serum together increased biofilm formation by seven different bacterial strains. In Staphylococcus aureus...

...Jie Ma; Erich Gulbins; Michael J. Edwards; Charles C. Caldwell; Martin Fraunholz; Katrin Anne Becker Background/Aims: Staphylococcus aureus ( S. aureus ) infections are a major clinical problem and range from mild skin and soft-tissue infections to severe and even lethal infections...

...Shaghayegh Tavakoli Tabazavareh; Aaron Seitz; Peter Jernigan; Carolin Sehl; Simone Keitsch; Stephan Lang; Barbara C. Kahl; Michael Edwards; Heike Grassmé; Erich Gulbins; Katrin Anne Becker Background: Pulmonary Staphylococcus aureus ( S. aureus ) infections occur early in a high percentage...

...Qianbo Chen; Tianyong Hou; Fei Luo; Xuehui Wu; Zhao Xie; Jianzhong Xu Background and Aims: Osteomyelitis is a common manifestation of invasive Staphylococcus aureus infection characterized by bone loss and destruction. We investigated the role of toll-like receptor 2 (TLR2) in bacterial recognition...

...Tao Jin; Yue liang Zhu; Jun Li; Jian Shi; Xiao qing He; Jing Ding; Yong qing Xu Background/Aims: Osteomyelitis is a debilitating infectious disease of the bone which is predominantly caused by Staphylococcus aureus (S. aureus) . The purpose of this study was to investigate the role of the S. aureus...

... improve the long-term viability of some antibiotics is important. In this study, we aimed to detect the suppressive effects of baicalein on the SOS system and rifampin-resistant mutation in Staphylococcus aureus . We determined the reactive oxygen species (ROS) formation and intracellular ATP level in S...