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Keywords: Sildenafil
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Cellular Physiology and Biochemistry (2011) 28 (4): 733–742.
Published Online: 14 December 2011
... i is GC-C/cGMP-mediated and enhanced by sildenafil, thus involving PDE5 enzyme. Additionally, cell exposure to apical UGN results in intracellular alkalinization, probably due to indirect effects on basolateral NHE1 and NHE4, which have a major role in pH i regulation. 26 08 2011 14 12...