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Keywords: STAT6
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Cellular Physiology and Biochemistry (2016) 38 (1): 153–159.
Published Online: 15 January 2016
... that protein kinase B (Akt) and signal transducer and activator of transcription (STAT)6 pathways were highly activated in IL-4/IL-1β-stimulated HPDLCs. Akt and STAT6 inhibitors decreased CCL11 production, but enhanced CCL20 production in HPDLCs stimulated with IL-4 and IL-1β. Conclusions: These results mean...
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Cellular Physiology and Biochemistry (2013) 32 (Suppl. 1): 238–248.
Published Online: 18 December 2013
... expression is increased following IL-4 and IL-13 exposure. The mechanism leading to increased pendrin expression is in part due to binding of STAT6 to a consensus sequence (N 4 GAS motif) located in the pendrin promoter. As retrospective analyses of the 5' upstream sequence of the human pendrin promoter...