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Keywords: RhoA
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Cellular Physiology and Biochemistry (2018) 50 (6): 2097–2107.
Published Online: 09 November 2018
...Liang Yang; Zhi-Fei Wang; Hao Wu; Wei Wang Background/Aims: MiRNAs may regulate neurogenic differentiation of adipose-derived stem cells (ADSCs). In this study, we hypothesized that the miR-142-5p can repress the expression of RhoA/ROCK1 pathway on the neurogenesis of ADSCs. Methods: Deregulated...
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Cellular Physiology and Biochemistry (2018) 47 (4): 1578–1588.
Published Online: 27 June 2018
..., and invasion, but decreased cell apoptosis through upregulating RhoA, YAP (Yes-associated protein), MMP2 (matrix metalloproteinase 2), Bcl-xL, and P70S6K expression; while PCGEM1 downregulation had the opposite effect. The nude mouse xenograft assay demonstrated that PCGEM1 overexpression promoted tumor growth...
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Journal Articles
Journal Articles
Cellular Physiology and Biochemistry (2016) 39 (4): 1391–1403.
Published Online: 08 September 2016
...Lei Zhang; Guoliang Jiang; Xueling Zhao; Yuekun Gong Background/Aims: We investigated the role of dimethyloxalylglycine (DMOG) in bone marrow mesenchymal stem cell (BMSC) osteogenesis mediated by RhoA/ROCK. Methods: BMSCs were cultured with and without DMOG and/or Y-27632 (ROCK1 inhibitor). Cell...
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Journal Articles
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Cellular Physiology and Biochemistry (2015) 35 (1): 246–258.
Published Online: 09 January 2015
... in neural cells. Methods: PC12 cells and primary cortical neurons (PCNs) were transfected with lenti-miR-133b, lenti-miR-133b inhibitor, plasmid-shRNA-RhoA, plasmid-RhoA and their negative controls. After 48 hours of transfection, the levels of proteins and mRNA or miRNA were evaluated by Western blotting...
Journal Articles
Journal Articles