... and intrasplenic BM-MSC transplantation on carbon tetrachloride (CCl 4 )-induced rat liver fibrosis. Methods: Fifty rats were divided into 5 groups (n = 10 rats per group): healthy control group, CCl 4 group, CCl 4 / recovery group, CCl 4 /BM-MSC intravenous group, and CCl 4 /BM-MSC intrasplenic group. BM-MSCs...

...Chuan Qin; Yun Guo; De-Gang Yang; Ming-Liang Yang; Liang-Jie Du; Jian-Jun Li Background/Aims: Spinal cord injury (SCI) has long been a subject of great interest in a wide range of scientific fields. Several attempts have been made to demonstrate motor function improvement in rats with SCI after...

...Zhuoqing Hu; Minqun Du; Wenxiu Lai; Yanlong Liang; Qin Liu; Yilin Mo; Jiaxin Bei; Shuhui Li; Yajun Yang; Jinrong Xu; Liao Cui Background/Aims: In this study we assessed histomorphometric changes induced by thyroxine (T4) in 3-month-old hyperthyroid male rats and examined whether the potential...

...Mohammed Al Za’abi; Suhail Al Salam; Yousuf Al Suleimani; Priyadarsini Manoj; Abderrahim Nemmar; Badreldin H. Ali Background/Aims: The effect of treatment with gum acacia (GA), a prebiotic shown previously to ameliorate chronic kidney disease (CKD), in diabetic and non – diabetic rats with adenine...

... colonic crypts has been studied, providing some insight into how Vitamin C achieve its effect. Methods: Distal colon was excised from rats. Following enzymatic digestion single colonic crypts were isolated. Colonic crypts were loaded with pH sensitive dye to measure the intracellular pH changes. Crypts...

... thoracic epidural anesthesia (HTEA) would reduce hippocampal apoptosis after global cerebral ischemia (GCI) injury. Methods: Fifteen-minute global ischemia was established by 4-vessel occlusion in adult male Wistar rats. And 0.5% bupivacaine or 0.9% saline (20 μl//h) was infused continuously...

...) has provided a new approach for the delivery of CO. In the present study, we examined whether the cardioprotective properties of CO-RM2 in isolated rat hearts subjected to an ischemia-reperfusion (I/R) sequence were associated with the presence of CO. In addition, the antioxidant properties of CO-RM2...

... of pressure on cellular growth and Src-dependent signaling pathways in the rat HSCs. Methods: Cultured rat HSCs were exposed to pressures (0 to 80 mmHg) by using a pressure-inducing apparatus. The proliferation of the cells was determined by a 5-bromo-2′-deoxy-uridine (BrdU) incorporation assay. Reverse...

...Yan-Zhou Zhang; Xiao-Wen Xing; Ben He; Le-Xin Wang Aims: To investigate the effects of testosterone treatment on cytokines, ventricular remodeling in rats with heart failure. Materials and methods: Sprague-Dawley male rats with heart failure were divided into testosterone (n = 22) and placebo (n...