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Keywords: Protein kinase CK2
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Journal Articles
Inhibition of Protein Kinase CK2 Closes the CFTR Cl - Channel, but has no Effect on the Cystic Fibrosis Mutant ΔF508-CFTR
Available to PurchaseSubject Area:
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Kate J. Treharne, Zhe Xu, Jeng-Haur Chen, O. Giles Best, Diane M. Cassidy, Dieter C. Gruenert, Péter Hegyi, Michael A. Gray, David N. Sheppard, Karl Kunzelmann, Anil Mehta
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2009) 24 (5-6): 347–360.
Published Online: 04 November 2009
... (SYDE) reported to control the pleiotropic protein kinase CK2. Methods: Electrophysiology, immunofluorescence and biochemistry applied to CFTR-expressing cells, Xenopus oocytes, pancreatic ducts and patient biopsies. Results: Irrespective of PKA activation, CK2 inhibition (ducts, oocytes, cells...