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Keywords: Parkin
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Journal Articles
Subject Area:
Further Areas
Cellular Physiology and Biochemistry (2018) 49 (5): 2022–2034.
Published Online: 21 September 2018
...Weiwei Xia; Jie Yin; Shuping Zhang; Chuchu Guo; Yuanyuan Li; Yue Zhang; Aihua Zhang; Zhanjun Jia; Hongbing Chen Background/Aims: Although a number of reports documented the important role of parkin in mitophagy, emerging evidence also indicated additional functions of parkin besides mitophagy...
Journal Articles
Subject Area:
Further Areas
Cellular Physiology and Biochemistry (2018) 48 (4): 1675–1693.
Published Online: 03 August 2018
.... At the molecular level, increased NR4A1 expression activated p53, and the latter selectively stimulated mitochondrial fission and inhibited mitophagy by modulating Mff and Parkin transcription. Excessive Mff-related mitochondrial fission caused mitochondrial oxidative stress, promoted mPTP opening, exacerbated...