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Keywords: PKC
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Cellular Physiology and Biochemistry (2018) 50 (1): 121–135.
Published Online: 02 October 2018
... by reducing the PKC-dependent AKT activity and elevating JNK phosphorylation. Since it was thought that GqPCR induces mainly activation of AKT, we undertook to examine how general is this phenomenon and understand its signaling. Methods: We used various cells to follow the phosphorylation of signaling...
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Cellular Physiology and Biochemistry (2017) 41 (3): 1156–1166.
Published Online: 28 February 2017
.... Hepatic fibrosis Diabetes PAR2 PAK PKC Astragaloside Cellular Physiology Cell Physiol Biochem 2017;41:1156-1166 and Biochemistry DOOII::1100.1.1115599/0/000464461421222 © 2017 The Autho©r(s2).0P1u7bTlihseheAdubthyoSr(.sK)arger AG, Basel Pubblliisshheeddoonnlilninee: F: eFberburaurayr2y82...
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Cellular Physiology and Biochemistry (2016) 40 (6): 1261–1273.
Published Online: 19 December 2016
.... Thus, we aimed to investigate the mechanisms by which α1-AR stimulation regulates I Kr . Methods: α1-adrenoceptors, hERG channels, auxiliary subunits minK and MIRP1, the non PIP 2 -interacting mutant D-hERG (with a deletion of the 883-894 amino acids) in the C-terminal and the non PKC-phosphorylable...
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Cellular Physiology and Biochemistry (2015) 36 (5): 1699–1711.
Published Online: 13 July 2015
... effect could be blocked by PKC or CaMKII inhibitors as well as EP1 receptor antagonist, and mimicked by PMA or EP1 receptor agonist. Furthermore, Western blot data showed that PGE 2 did not increase the total expression level of GABA A receptors, but significantly increased surface levels of GABA A β1/2...
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Cellular Physiology and Biochemistry (2012) 29 (5-6): 725–736.
Published Online: 11 May 2012
... binding sites exerted negative effects on the cox-2 promoter activity. Among the signaling components of FcHRI, Fyn, PI 3-kinase, Akt, and p38 MAPK positively mediated the COX-2 expression. Conventional PKCs and atypical PKCs exerted opposite regulatory effects on the cox-2 promoter activity. Blockade...
Journal Articles
Cellular Physiology and Biochemistry (2012) 29 (1-2): 1–8.
Published Online: 01 March 2012
... Sepsis Phagocytosis Cytokines NF-ĸB MAPK Akt PKC Insulin Diabetes Mellitus Alveolar macrophages Cellular Physiology and Biochemistry Review Cell Physiol Biochem 2012;29:01-08 Accepted: November 21, 2011 Briefs on Insulin and Innate Immune Response Karen K. S. Sunahara1, Paulina Sannomiya2...
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Cellular Physiology and Biochemistry (2012) 29 (1-2): 269–280.
Published Online: 01 March 2012
...-induced pericellular hypoxia and CoCl 2 -induced hypoxia, specific inhibitors of p38 MAPK could concentration-dependently block those effects of hypoxia on AQP1 expression. Intracellular calcium ion (Ca 2+ ) and protein kinase C (PKC) were shown to be responsible for the activation of p38 MAPK pathway...
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Cellular Physiology and Biochemistry (2011) 28 (4): 703–714.
Published Online: 14 December 2011
...Zheng Wang; Victor N. Bildin; Hua Yang; José E. Capó-Aponte; Yuanquan Yang; Peter S. Reinach Epidermal growth factor (EGF) receptor stimulation or protein kinase C (PKC) activation enhances corneal epithelial cell proliferation. This response is needed to maintain corneal transparency and vision...
Journal Articles
Cellular Physiology and Biochemistry (2010) 26 (4-5): 739–748.
Published Online: 29 October 2010
... of signaling pathways. Results: Relative to non-diabetic rats, the diabetic rats exhibited a significant reduction in OA-induced phosphorylation of the extracellular signal-regulated kinase (ERK, 59%), p38 (53%), protein kinase B (Akt, 46%), protein kinase C (PKC)- α (63%) and PKC-δ (38%) in lung homogenates...
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Cellular Physiology and Biochemistry (2009) 24 (5-6): 441–450.
Published Online: 04 November 2009
... ethanol stimulation in either treatment. Conclusion: Signaling of ethanol-induced insulin secretion from INS-1 and INS-1E cell lines bypasses calcium and PKC involving steps, is sensitive to tetanus toxin but resistant to N-ethymaleimide and ZnCl 2 . An extra pool of secretory vesicles not available...
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Cellular Physiology and Biochemistry (2009) 23 (1-3): 053–064.
Published Online: 18 February 2009
... intracellular Ca 2+ levels via regulation of phospholipase C (PLC) and activated protein kinase C (PKC). LA activated phosphatidylinositol 3-kinase (PI3K)/Akt and p44/42 mitogen-activated protein kinases (MAPKs). U73122 (PLC inhibitor), staurosporine (PKC inhibitor), LY294002 (PI3K inhibitor), and Akt inhibitor...
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Cellular Physiology and Biochemistry (2008) 22 (5-6): 715–724.
Published Online: 09 December 2008
... MAPKs PKA PKC Sugar Cellular Physiology and Biochemistry Original Paper Cell Physiol Biochem 2008;22:715-724 Accepted: September 02, 2008 Lipopolysaccharide Induces Inhibition of Galactose Intestinal Transport in Rabbits in vitro Pilar Amador1, M. Carmen Marca2,5, Josefina García-Herrera1, M...
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Cellular Physiology and Biochemistry (2008) 22 (5-6): 673–684.
Published Online: 09 December 2008
... of IL-6Rα and glycoprotein (gp) 130 (IL-6Rβ) protein expression, Janus Kinase (JAK) 2, signal transducer and activator of transcription (STAT) 3, PKC, p44/42 MAPKs phosphorylation, and PPARδ protein expression. Inhibition of each pathways blocked IL-6-induced [ 3 H]thymidine incorporation increase. IL-6...
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Cellular Physiology and Biochemistry (1997) 7 (3-4): 159–171.
Published Online: 04 September 2008
...L.C. Schlichter; I. Chung; M.C. Chang Voltage-activated Kv1.3 channels, which are involved in normal functions of human T lymphocytes, contain consensus sites for phosphorylation by PKA, PKC, and CaMKII. Because T-cell functions often depend on second-messenger pathways involving serine/threonine...
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Cellular Physiology and Biochemistry (2008) 21 (4): 297–304.
Published Online: 23 April 2008
... MAPK, PI3K and PKCs and inhibits a downstream effect of LPS, TNF production, in rat AMs stimulated with LPS and suggest that the protective effect of insulin in sepsis could be through modulation of signal transduction pathways elicited by LPS in lung macrophages. Cellular Physiology and Biochemistry...
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Cellular Physiology and Biochemistry (2006) 20 (1-4): 143–156.
Published Online: 22 May 2007
... R -hydroxy-5, 8, 14- cis -10- trans -eicosatetraenoic acid, and LTD 4 did not activate mBLT1. U75302, specifically targeting BLT1, significantly reduced LTB 4 -evoked Cl - currents. Repetitive LTB 4 administration desensitized the LTB 4 -evoked currents. Activation of protein kinase C (PKC) by PMA...
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