... in the PI3K-AKT pathway were determined using western blot analysis and immunoblotting. Results: The expression of protein phosphatase 2A was significantly upregulated in the clinical specimens of high-grade MECs compared with those of low-/medium-grade MECs and normal controls. In this article, we report...

...: Troxerutin preconditioning protected against myocardial I/R injury via the PI3K/Akt pathway. The H9c2 cells, a rat cardiomyoblast line, were purchased from American Type Culture Collection (Manassas, VA, USA). The cell lines had been passaged for less than 6 months when used for experiments. H9c2 cells...

... suppressed the expression of VEGF at both the mRNA and protein levels and decreased HIF-1α protein expression. HIF-1α activation was regulated by the PI3K/AKT pathway. The celecoxib-induced down-regulation of HIF-1α and VEGF required the suppression of the hypoxia-induced PI3K/AKT pathway. However, the down...

..., the effects of didymin on hepatic stellate cell apoptosis and cell cycle were analyzed by flow cytometry. Mitochondrial membrane potential was detected by using rhodamine-123 dye. The expression of Raf kinase inhibitor protein (RKIP) and the phosphorylation of the ERK/MAPK and PI3K/Akt pathways were assessed...

... and a Student's t-test using the SPSS 11.5 software package. All of the P-values were two-sided, and P<0.05 was considered to indicate a statistically significant difference. ART1 shRNA Apoptosis PI3K/Akt pathway Bcl-2 Colorectal carcinoma is a major cause of cancer death in affluent countries...

... signaling pathway. 16 01 2012 3 4 2012 PARG PARP shRNA PI3K/Akt pathway NF-ĸB MMP2 MMP9 Metastasis © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages...