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Keywords: P-glycoprotein (P-gp)
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Journal Articles
Subject Area:
Further Areas
Wei Liu, Qiang Meng, Yaoting Sun, Changyuan Wang, Xiaokui Huo, Zhihao Liu, Pengyuan Sun, Huijun Sun, Xiaodong Ma, Kexin Liu
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (4): 1616–1631.
Published Online: 29 November 2018
...Wei Liu; Qiang Meng; Yaoting Sun; Changyuan Wang; Xiaokui Huo; Zhihao Liu; Pengyuan Sun; Huijun Sun; Xiaodong Ma; Kexin Liu Background/Aims: The emergence of multidrug resistance (MDR) caused by P-glycoprotein (P-gp) overexpression is a serious obstacle to the treatment of chronic myelocytic...
Journal Articles
Subject Area:
Further Areas
Guinever Eustaquio do Imperio, Enrrico Bloise, Mohsen Javam, Phetcharawan Lye, Andrea Constantinof, Caroline Dunk, Fernando Marcos dos Reis, Stephen James Lye, William Gibb, Tania M. Ortiga-Carvalho, Stephen Giles Matthews
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 45 (2): 591–604.
Published Online: 29 January 2018
... using TaqMan® Human ABC Transporter Array, in preterm human placentas without (PTD; n=6) or with histological chorioamnionitis (PTDC; n=6). Validation was performed using qPCR, immunohistochemistry and Western blot. MicroRNAs known to regulate P-glycoprotein (P-gp) were examined by qPCR. Results: Up...
Journal Articles
Subject Area:
Further Areas
Enrrico Bloise, Sophie Petropoulos, Majid Iqbal, Alisa Kostaki, Tania Maria Ortiga-Carvalho, William Gibb, Stephen G. Matthews
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (3): 1044–1050.
Published Online: 22 February 2017
... known to elicit adverse fetal neurological outcomes. The P-glycoprotein (P-gp) efflux transporter protects the developing fetus by limiting the transfer of substrates across both the placenta and the fetal blood-brain barrier (BBB). As such, inhibition of P-gp at these blood-barrier sites may result...