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Keywords: Oxidative stressClose
Cellular Physiology and Biochemistry (2018) 51 (5): 2341–2358.
Published Online: 07 December 2018
... superovulation significantly decreased ovarian function and oocyte quality and increased oxidative stress and apoptosis in the ovary via a mechanism involving the p16 and SIRT1/FOXO1 signaling pathways. These findings suggest that consecutive superovulation may be used to establish a mouse model of ovarian aging...
Cellular Physiology and Biochemistry (2018) 51 (5): 1996–2009.
Published Online: 06 December 2018
.... Erythrocytes are lacking mitochondria and nuclei, key organelles of apoptosis but are, similar to apoptosis of nucleated cells, able to enter suicidal erythrocyte death or eryptosis. Stimulators of eryptosis include energy depletion, hyperosmotic shock, oxidative stress, and increase of cytosolic Ca 2...
Cellular Physiology and Biochemistry (2018) 51 (4): 1908–1920.
Published Online: 30 November 2018
... K6PC-5 SphK1 Nrf2 Oxidative stress During the pathogenesis of stroke, ischemia-reperfusion can severely damage neurons [ 1, 2 ]. Ischemia-reperfusion injury can be mimicked in cultured neuronal cells using oxygen glucose deprivation and re-oxygenation (OGDR) [ 3-6 ]. OGDR-induced neuronal...
Cellular Physiology and Biochemistry (2018) 51 (1): 201–216.
Published Online: 16 November 2018
... (NAC) in diabetes have been reported in many therapeutic studies. NAC has been shown to reduce oxidative stress and enhance redox potential in tissues protecting them against oxidative stress associated complications in diabetes. In the current study, we aimed to investigate the molecular mechanisms...
Yuping Liu, Yang Zhao, Zhonghong Wei, Li Tao, Xiaobo Sheng, Siliang Wang, Jiao Chen, Junshan Ruan, Zhaoguo Liu, Yuzhu Cao, Yunlong Shan, Aiyun Wang, Wenxing Chen, Yin Lu
Cellular Physiology and Biochemistry (2018) 50 (5): 1945–1963.
Published Online: 05 November 2018
... and the counts were averaged [ 29 ]. DATS Metastatic breast cancer Oxidative stress Thioredoxin system Trx-1 Garlic ( Allium ) has been employed as a flavouring and medicinal agent for hundreds of years. Epidemiological studies have indicated an inverse correlation between garlic consumption...
Cellular Physiology and Biochemistry (2018) 50 (3): 841–850.
Published Online: 24 October 2018
... (GM)-induced cytotoxicity in HEK293 cells, and investigated the effect of SDAPR against GM-induced nephrotoxicity in mice. Methods: HEK293 cells viability and oxidative stress were measured in HEK293 cells while flow cytometry was used for apoptosis analysis. The acute kidney injury biomarkers, kidney...
Jun-Hui Yang, Run-Jiao Zhang, Jia-Jie Lin, Ming-Chao Cao, Qie Wang, Hui-Xian Cui, Shao-Guang Sun, Lei Wang
Cellular Physiology and Biochemistry (2018) 50 (3): 936–951.
Published Online: 24 October 2018
... neurodegeneration-related oxidative stress. Circular RNAs (circRNAs) are involved with various diseases in the central nervous system (CNS). This study aimed to identify the key circRNAs involved in Nrf2-neuroprotection against oxidative stress. Methods: The differentially expressed circRNAs (DEcircRNAs...
Ping Zhang, Shan Zhong, Guang Wang, Shi-yao Zhang, Chang Chu, Shufei Zeng, Yu Yan, Xin Cheng, Yongping Bao, Berthold Hocher, Xuesong Yang
Cellular Physiology and Biochemistry (2018) 49 (6): 2483–2495.
Published Online: 27 September 2018
...-Nrf2 signaling and oxidative stress key enzyme gene expressions (SOD, GPx and YAP1). Conclusion: We established a LPS-induced angiogenesis model in chick CAM. NAC administration could effectively inhibit LPS-induced angiogenesis and restore the integrity of endothelium on chick CAM. LPS exposure caused...
Cellular Physiology and Biochemistry (2018) 49 (6): 2320–2332.
Published Online: 27 September 2018
... genes, and it is an upstream regulator of the encoding of antioxidative proteins, such as heme oxygenase 1 (HO-1), which antagonize reactive oxygen species (ROS)-induced oxidative stress [ 7, 8 ]. Salvianolic acid A (SalA) is a water-soluble component that is extracted from the dried root...
Cellular Physiology and Biochemistry (2018) 49 (6): 2200–2213.
Published Online: 26 September 2018
...Qinghai Chen; Shiliang Yu; Kuo Zhang; Zuobiao Zhang; Chao Li; Bingpeng Gao; Weihua Zhang; Yan Wang Background/Aims: The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular...
Cellular Physiology and Biochemistry (2018) 49 (4): 1577–1588.
Published Online: 17 September 2018
... transmission electron microscopy (TEM), hemolysis, and colorimetric measurement of markers of oxidative stress comprising malondialdehyde (MDA), reduced glutathione (GSH), and catalase (CAT). Intracellular calcium (Ca 2+ ) was determined using Fura 2AM fluorescence. Annexin V was quantified using ELISA...
Jing Yang, Hong-shan Yin, Ya-jing Cao, Zhi-an Jiang, Yong-jun Li, Mu-chun Song, Yong-fei Wang, Zhi-hua Wang, Rong Yang, Yun-fa Jiang, Jin-peng Sun, Bo-yi Liu, Chuan Wang
Cellular Physiology and Biochemistry (2018) 49 (2): 728–742.
Published Online: 30 August 2018
... with attenuating oxidative stress by Nrf2 signaling pathway. Fig. 1. Representative examples of different ventricular arrhythmias during the 30 min ischemia. VT, ventricular tachycardia; VF, ventricular fibrillation Fig. 1. Representative examples of different ventricular arrhythmias during the 30 min...
Cellular Physiology and Biochemistry (2018) 49 (1): 101–122.
Published Online: 28 August 2018
... was detected by quantitative real-time polymerase chain reaction (qRT-PCR), HO-1 expression and enzymatic activity in PVECs and the influence of zinc protoporphyrin (ZnPP) or HO-1 small interfering RNA on the above inflammatory and oxidative stress markers were evaluated. In addition, the expression of rat MSC...
Yixiu Zhao, Xin Zhang, Jing Luan, Buchang Zhao, Na An, Na Sun, Xinhui Wang, Tao Zhao, Yanhong Sun, Zidong Donna Fu, Yan Zhang, Yan Zhang
Cellular Physiology and Biochemistry (2018) 48 (6): 2503–2516.
Published Online: 17 August 2018
... Bradyarrhythmia Oxidative stress SXSM (Batch No. 150601) used in this study was provided by Buchang Phamaceutical Co., LTD (Heze, China, Patent No. ZL200710019161.5). SXSM comprises eight herbal medicines, including Panax ginseng C. A. Mey. (Araliaceae), Epimedium brevicornu Maxim (Berberidaceae...
Ling-Fang Wang, Cong-Cong Huang, Yun-Fei Xiao, Xiao-Hui Guan, Xiao-Nv Wang, Qing Cao, Yu Liu, Xuan Huang, Li-Bin Deng, Ke-Yu Deng, Hong-Bo Xin
Cellular Physiology and Biochemistry (2018) 48 (6): 2350–2363.
Published Online: 16 August 2018
... after OA stimulation. Conclusion: Our results demonstrated that CD38 deficiency protected heart from HFD-induced oxidative stress via activating Sirt3/FOXO3-mediated anti-oxidative stress pathway. email@example.com 22 08 2017 6 08 2018 16 8 2018 Cd38 Oxidative stress...
Zi Wang, Yan-fei Li, Xin-yue Han, Yin-shi Sun, Lian-xue Zhang, Wei Liu, Xiang-xiang Liu, Wei Li, Ying-ying Liu
Cellular Physiology and Biochemistry (2018) 48 (5): 2219–2229.
Published Online: 15 August 2018
... injection of CDDP (25 mg/kg) was given at 1 h after G-Re treatment. Results: CDDP administration resulted in renal dysfunction, as evidenced by an increase in the serum levels of creatinine and urea nitrogen. Oxidative stress in the CDDP group was reflected by an increase of malondialdehyde and a depletion...
Cellular Physiology and Biochemistry (2018) 48 (5): 1815–1828.
Published Online: 09 August 2018
..., instructions or products referred to in the content or advertisements. Hydrogen sulfide Nuclear factor erythroid 2-related factor 2 Oxidative stress Placental damage Redox imbalance Cigarette smoke is one of the major environmental health risk factors affecting almost all the organs...
Ningning Zheng, Xudong Ding, Dan Wei, Bo Dai, Lanyan Zheng, Ryo Sumi, Dahai Hu, Rabita Jahane, Luning Sun
Cellular Physiology and Biochemistry (2018) 48 (4): 1519–1529.
Published Online: 02 August 2018
... indices were measured using enzymatic colorimetric kits. A biologic data acquisition and analysis system (BL-420F) was used to evaluate cardiac function. Expression of mitochondrial respiratory chain (MRC) enzymes was measured by immunofluorescence staining. The proteins associated with oxidative stress...
Cellular Physiology and Biochemistry (2018) 48 (4): 1468–1479.
Published Online: 31 July 2018
...-induced human umbilical vein endothelial cells (HUVECs) injury were evaluated by Cell Counting Kit-8 (CCK-8) assay and released lactic dehydrogenase (LDH) activity assay. Oxidative stress was determined by malonedialdehyde (MDA) content and superoxide dismutase (SOD) activity. The level of reactive oxygen...
Cellular Physiology and Biochemistry (2018) 48 (3): 1369–1381.
Published Online: 26 July 2018
..., and higher RSNA. ExT attenuated these changes in salt-induced hypertensive rats. Conclusions: These findings suggest that high salt diet increases the activity of NF-κB and the levels of PIC and oxidative stress, and induces an imbalance between excitatory and inhibitory neurotransmitters in the RVLM. ExT...