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Keywords: Oxidative stress
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Cellular Physiology and Biochemistry (2018) 51 (5): 2341–2358.
Published Online: 07 December 2018
... superovulation significantly decreased ovarian function and oocyte quality and increased oxidative stress and apoptosis in the ovary via a mechanism involving the p16 and SIRT1/FOXO1 signaling pathways. These findings suggest that consecutive superovulation may be used to establish a mouse model of ovarian aging...
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Cellular Physiology and Biochemistry (2018) 51 (5): 1996–2009.
Published Online: 06 December 2018
.... Erythrocytes are lacking mitochondria and nuclei, key organelles of apoptosis but are, similar to apoptosis of nucleated cells, able to enter suicidal erythrocyte death or eryptosis. Stimulators of eryptosis include energy depletion, hyperosmotic shock, oxidative stress, and increase of cytosolic Ca 2...
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Cellular Physiology and Biochemistry (2018) 51 (4): 1908–1920.
Published Online: 30 November 2018
... or advertisements. Neuron K6PC-5 SphK1 Nrf2 Oxidative stress During the pathogenesis of stroke, ischemia-reperfusion can severely damage neurons [ 1, 2 ]. Ischemia-reperfusion injury can be mimicked in cultured neuronal cells using oxygen glucose deprivation and re-oxygenation (OGDR) [ 3-6 ]. OGDR...
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Cellular Physiology and Biochemistry (2018) 50 (3): 841–850.
Published Online: 24 October 2018
... (GM)-induced cytotoxicity in HEK293 cells, and investigated the effect of SDAPR against GM-induced nephrotoxicity in mice. Methods: HEK293 cells viability and oxidative stress were measured in HEK293 cells while flow cytometry was used for apoptosis analysis. The acute kidney injury biomarkers, kidney...
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Cellular Physiology and Biochemistry (2018) 50 (3): 936–951.
Published Online: 24 October 2018
... neurodegeneration-related oxidative stress. Circular RNAs (circRNAs) are involved with various diseases in the central nervous system (CNS). This study aimed to identify the key circRNAs involved in Nrf2-neuroprotection against oxidative stress. Methods: The differentially expressed circRNAs (DEcircRNAs...
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Cellular Physiology and Biochemistry (2018) 49 (6): 2483–2495.
Published Online: 27 September 2018
...-Nrf2 signaling and oxidative stress key enzyme gene expressions (SOD, GPx and YAP1). Conclusion: We established a LPS-induced angiogenesis model in chick CAM. NAC administration could effectively inhibit LPS-induced angiogenesis and restore the integrity of endothelium on chick CAM. LPS exposure caused...
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Cellular Physiology and Biochemistry (2018) 49 (4): 1577–1588.
Published Online: 17 September 2018
... transmission electron microscopy (TEM), hemolysis, and colorimetric measurement of markers of oxidative stress comprising malondialdehyde (MDA), reduced glutathione (GSH), and catalase (CAT). Intracellular calcium (Ca 2+ ) was determined using Fura 2AM fluorescence. Annexin V was quantified using ELISA...
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Cellular Physiology and Biochemistry (2018) 48 (5): 2219–2229.
Published Online: 15 August 2018
... injection of CDDP (25 mg/kg) was given at 1 h after G-Re treatment. Results: CDDP administration resulted in renal dysfunction, as evidenced by an increase in the serum levels of creatinine and urea nitrogen. Oxidative stress in the CDDP group was reflected by an increase of malondialdehyde and a depletion...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1519–1529.
Published Online: 02 August 2018
... indices were measured using enzymatic colorimetric kits. A biologic data acquisition and analysis system (BL-420F) was used to evaluate cardiac function. Expression of mitochondrial respiratory chain (MRC) enzymes was measured by immunofluorescence staining. The proteins associated with oxidative stress...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1468–1479.
Published Online: 31 July 2018
...-induced human umbilical vein endothelial cells (HUVECs) injury were evaluated by Cell Counting Kit-8 (CCK-8) assay and released lactic dehydrogenase (LDH) activity assay. Oxidative stress was determined by malonedialdehyde (MDA) content and superoxide dismutase (SOD) activity. The level of reactive oxygen...
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