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Keywords: Ovarian Cancer
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Cellular Physiology and Biochemistry (2018) 51 (1): 129–141.
Published Online: 15 November 2018
...Ying Jiang; Jing Jiang; Haiqing Jia; Zhiwei Qiao; Jingru Zhang Background/Aims: In platinum-based chemotherapy for ovarian cancer, acquired drug resistance is a frequent occurrence. Because recent studies have demonstrated that dysregulation of microRNAs (miRNAs) is partly responsible...
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Cellular Physiology and Biochemistry (2018) 50 (1): 214–232.
Published Online: 18 October 2018
.... Its integrity is maintained by simple desmosomes, incomplete tight junctions, several integrins and cadherins. Recent research has found that ovarian stem cells (OSCs) exist within the OSE and may be responsible for both neo-oogenesis and ovarian cancer during adult life. The factors determining...
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Cellular Physiology and Biochemistry (2018) 49 (5): 1766–1777.
Published Online: 19 September 2018
... upregulation of vimentin, among other biomarkers. We have found FSCN1 promoted EMT in ovarian cancer cells, but the precise mechanism of FSCN1 in EMT process has not been clearly elucidated. Methods: The levels of FSCN1 and snail1 were determined in epithelial ovarian cancer(EOC) specimen and in ovarian cancer...
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Cellular Physiology and Biochemistry (2018) 49 (4): 1289–1303.
Published Online: 11 September 2018
...Lei Chang; Ruixia Guo; Zhongfu Yuan; Huirong Shi; Dongya Zhang Background/Aims: The long noncoding RNA homeobox (HOX) transcript antisense intergenic RNA (HOTAIR) has been demonstrated to be a vital modulator in the proliferation and metastasis of ovarian cancer cells, but its potential molecular...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1505–1518.
Published Online: 02 August 2018
...Xinfeng Liu; Ying Yu; Jinna Zhang; Caixia Lu; Liming Wang; Ping Liu; Hao Song Background/Aims: Cisplatin-based treatment is first-line chemotherapy for several cancers including ovarian cancer. The development of cisplatin resistance results in treatment failure, but the underlying mechanisms...
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Cellular Physiology and Biochemistry (2018) 47 (4): 1578–1588.
Published Online: 27 June 2018
... in epithelial ovarian cancer is unknown. Methods: PCGEM1 expression was examined in epithelial ovarian cancer and normal ovarian tissues using reverse transcription–PCR. Ovarian cancer cell phenotypes and genotypes were examined after PCGEM1 overexpression or downregulation in vitro ; besides, the effects...
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Cellular Physiology and Biochemistry (2018) 45 (4): 1654–1662.
Published Online: 21 February 2018
...Yang Liu; Jie Lin; Shujuan Zhai; Chunyi Sun; Changjun Xu; Honglin Zhou; Huijin Liu Background/Aims: Ovarian cancer is one of the most common malignancies with a high rate of mortality in women. However, current therapies for ovarian cancer treatment are ineffective. Therefore, novel target...
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Cellular Physiology and Biochemistry (2018) 45 (3): 1061–1071.
Published Online: 07 February 2018
...Shengyun Cai; Pei Zhang; Suhe Dong; Li Li; Jianming Cai; Mingjuan Xu Background/Aims: Ovarian cancer (OC) is the fifth leading cause of cancer-related death in women, and it is difficult to diagnose at an early stage. The purpose of this study was to explore the prognostic biological markers of OC...
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Cellular Physiology and Biochemistry (2017) 44 (3): 948–966.
Published Online: 27 November 2017
... networks in tumorigenesis. LncRNAs are considered important factors in several ovarian cancer histotypes, although few have been identified and characterized. Owing to their complexity and the lack of adapted molecular technology, the roles of most lncRNAs remain mysterious. Some lncRNAs have been reported...