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Keywords: Osteosarcoma
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Cellular Physiology and Biochemistry (2018) 51 (4): 1879–1893.
Published Online: 30 November 2018
...Zheng Xiao; Jia Wan; Ayub Abdulle Nur; Pencheng Dou; Henry Mankin; Tang Liu; Zhengxiao Ouyang Background/Aims: Drug resistance is the main difficulty for the current treatment for osteosarcoma. Cluster of differentiation 44 (CD44) is a receptor for hyaluronic acid (HA) and HA-binding has been...
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Cellular Physiology and Biochemistry (2018) 51 (2): 938–948.
Published Online: 22 November 2018
...Yazeng Huang; Jun Zhang; Haiyu Shao; Jianwen Liu; Mengran Jin; Jinping Chen; Hongying Zhao Background/Aims: Preventing cell metastasis is an effective therapeutic strategy to treat osteosarcoma and improve prognosis. Statins have been found to have anticancer effects in addition...
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Cellular Physiology and Biochemistry (2018) 50 (6): 2249–2259.
Published Online: 13 November 2018
...Xuesong Wang; Lei Peng; Xiaojin Gong; Xiugong Zhang; Ruifu Sun; Jinlong Du Background/Aims: Increasing evidences suggest that dysregulated expression of miRNAs contributes to the progression of various tumors. However, the underlying function of miR-423-5p in osteosarcoma remains unexplored...
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Journal Articles
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Cellular Physiology and Biochemistry (2018) 46 (6): 2250–2260.
Published Online: 03 May 2018
...Chunming Jiang; Shenglin Ma; Runlei Hu; Xuepeng Wang; Maoqiang Li; Fei Tian; Wu Jiang; Liulong Zhu; Zhenyu Bian Background/Aims: Osteosarcoma, the most common primary bone malignancy, arises from primitive transformed cells of mesenchymal origin with the worldwide increasing morbidity and mortality...
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Cellular Physiology and Biochemistry (2018) 46 (3): 1218–1230.
Published Online: 16 April 2018
...Tang Liu; Zuyun Yan; Yong Liu; Edwin Choy; Francis J. Hornicek; Henry Mankin; Zhenfeng Duan Background/Aims: Metastasis is the major cause of death in patients with osteosarcoma. There is an urgent need to identify molecular markers that promote metastasis. Cluster of differentiation 44...
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Cellular Physiology and Biochemistry (2018) 46 (3): 1134–1147.
Published Online: 13 April 2018
...Guo Dai; Di Zheng; Weichun Guo; Jian Yang; An-yuan Cheng Background/Aims: Osteosarcoma is a common primary malignant bone tumor that mainly occurs in childhood and adolescence. Despite developments in the diagnosis and treatment of osteosarcoma, the prognosis is still very poor. Cinobufagin...
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Cellular Physiology and Biochemistry (2018) 46 (2): 442–450.
Published Online: 26 March 2018
... and function in osteosarcoma. Methods: Expression of miR-330-3p in osteosarcoma tissues and cell lines was examined by quantitative PCR. Effects of miR-330-3p on osteosarcoma cell proliferation were investigated in vitro with the Cell Counting Kit-8 colorimetric assay. Targets of miR-330-3p were identified...
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Cellular Physiology and Biochemistry (2018) 45 (5): 1904–1914.
Published Online: 02 March 2018
...Hui Ye; Jinkuang Lin; Xuedong Yao; Yizhong Li; Xiaobin Lin; Hai Lu Background/Aims: Increasing evidence demonstrates that long non-coding RNAs (lncRNAs) play critical regulatory roles in cancers, including osteosarcoma. A previous study showed that Nicotinamide Nucleotide Transhydrogenase-antisense...
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Cellular Physiology and Biochemistry (2018) 45 (5): 1966–1974.
Published Online: 02 March 2018
... to uncover the mechanism of tumour suppression by miR-194. The expression of miR-194 in osteosarcoma cell lines and tissues were monitored by real-time PCR. Methods: The proliferation ability was examined by MTT assay. Migration and apoptosis of cells were monitored by migration assay and flow cytometry...
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Cellular Physiology and Biochemistry (2018) 45 (2): 808–818.
Published Online: 31 January 2018
...Zhong Wu; Jie Liu; Siyuan Hu; Yuchang Zhu; Shaohua Li Background/Aims: Serine/threonine kinase 35 (STK35) may be associated with Parkinson disease and human colorectal cancer, but there have been no reports on the expression levels or roles of STK35 in osteosarcoma. Methods: STK35 mRNA expression...
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Journal Articles
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Cellular Physiology and Biochemistry (2017) 43 (2): 768–774.
Published Online: 27 September 2017
...Tieying Tao; Qinrong Shen; Jianmin Luo; Yang Xu; Wenqing Liang Background/Aims: Increasing evidence has shown that miR-125a plays important role in human cancer progression. However, little is known about the function of miR-125a in osteosarcoma. Methods: The expression of miR-125a in osteosarcoma...
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Cellular Physiology and Biochemistry (2017) 43 (2): 553–567.
Published Online: 21 September 2017
...Haifeng Lan; Wei Hong; Pan Fan; Dongyang Qian; Jianwei Zhu; Bo Bai Background/Aims: Osteosarcoma is a malignant tumor associated with high mortality; however, no effective therapies for the disease have been developed. Several studies have focused on elucidating the pathogenesis of osteosarcoma...
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Cellular Physiology and Biochemistry (2017) 42 (5): 1812–1821.
Published Online: 27 July 2017
...Jilong Zou; Yan Zhang; Jiabing Sun; Xiaoyan Wang; Hualei Tu; Shuo Geng; Renhao Liu; Yuxi Chen; Zhenggang Bi Background/Aims: Osteosarcoma is the predominant form of primary bone malignancy. Although the combinational application of neoadjuvant chemotherapy and surgical resection significantly...
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Cellular Physiology and Biochemistry (2017) 42 (4): 1407–1419.
Published Online: 17 July 2017
...Zhihong Li; Pengcheng Dou; Tang Liu; Shasha He Osteosarcoma is the most common primary bone malignancy in children and adolescents. Although improvements in therapeutic strategies were achieved, the outcome remains poor for most patients with metastatic or recurrent osteosarcoma. Therefore...
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Cellular Physiology and Biochemistry (2017) 41 (5): 1935–1946.
Published Online: 07 April 2017
...Lin Fan; Chunyan Zhu; Rongmin Qiu; Pengfei Zan; Zhi Zheng; Tianyang Xu; Guodong Li Aim: Osteosarcoma (OS) is an aggressive bone malignancy that affects rapidly growing bones and is associated with a poor prognosis. Our previous study showed that cytochrome c1 (CYC1), a subunit of the cytochrome bc1...
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