.... Intracellular lipid contents and lipogenic gene expression were determined by enzymatic colorimetric assays and real-time PCR, respectively. Inflammatory status was evidenced by Western blot analysis for the phosphorylation of nuclear factor-κB (NF-κB) p65 and real-time PCR analysis for the expression of pro...

... kinase Nuclear factor-κB © 2018 The Author(s). Published by S. Karger AG, Basel 2018 Open Access License / Drug Dosage / Disclaimer This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND). Usage and distribution...

.... Atherosclerosis ATP-binding cassette transporter A1 Inflammation Toll-like receptor 4 Nuclear factor-κB Cardiovascular disease (CVD) is one of the common causes of mortality around the world [ 1 ], the pathophysiological foundation of which is atherosclerosis (AS) [ 2 ]. AS is widely considered...

.... Nonalcoholic fatty liver disease (NAFLD) Free fatty acid (FFA) High fat diet (HFD) Autophagy Ghrelin Nuclear factor-κB Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. The prevalence of NAFLD in adults in the US is currently estimated at ≤46% [ 1...

... at 72 h and applied as source of the pressed protein (PLV-PTPRO-GFP). PLV-PTPRO-GFP plasmid was transfected to 0.5-1.0×10 6 RAW264.7 cells accompanied with polybrene reagent. Fulminant hepatitis Nuclear factor-κB Protein tyrosine phosphatase receptor type O Toll-like receptor 4 Spleen...

... controls were detected by enzyme-linked immunosorbent assay (ELISA) or western blot assay, respectively. RAW264.7 cells were stimulated by lipopolysaccharide (LPS) and/or IL-29. The production of inflammatory cytokines including IL-6, IL-8 as well as TNF-a and the activation of nuclear factor-κB (NF-κB...

... Interleukin-6 Tumor necrosis factor-α Toll-like receptor 4 Nuclear factor-κB Many complications result from the metabolic disorders of diabetes mellitus (DM) [ 1 ]. Oxidative stress and inflammation play crucial roles in the progression of DM [ 2 ]. The study conducted by Fumei Tang revealed...

... mitogen-activated protein kinase (MAPK) pathway and that the p38 MAPK/nuclear factor-κB (NF-κB) pathway is involved in the DOX-induced inflammatory response and cytotoxicity. The present study attempts to test the hypothesis that exogenous H 2 S might protect cardiomyocytes against the DOX-induced...