.... Significantly decreased expression levels of capspase-3 in DRG neurons, and increased (Na + -K + ) ATPase activity in sciatic nerves, were observed. In addition, deguelin decreased glucose levels, attenuated oxidative stress and neuroinflammation, and elevated levels of H 2 S, nuclear respiratory factor 2 (Nrf2...

...-neuroinflammatory and anti-oxidative effects of StA may show preventive therapeutic potential for various neuroinflammatory disorders. Schisantherin A Neuroinflammation Microglia Nrf2 NF-κB Neuroinflammation is an inevitable and important pathological process involved in all types of damage...

..., methods, instructions or products referred to in the content or advertisements. Trem2 Microglia Cytokines Hippocampus Neuroinflammation Postoperative Cognitive Dysfunction (POCD) Postoperative cognitive dysfunction (POCD) is characterized by the progressive deterioration of intellectual...

...Xiang Zhang; Hao Yao; Qingqing Qian; Nana Li; Wenjie Jin; Yanning Qian Background: Astrocytes, the major glial cell type that has been increasingly recognized as contributing to neuroinflammation, are critical in the occurrence and development of postoperative cognitive dysfunction (POCD). Although...

... to play a major role in the recruitment of inflammatory cells to sites of tissue injury [ 15,16 ], and the expression of CCR2 has been demonstrated in microglia [ 17 ]. Recently it was reported that astrocytes are the main source of CCL2 in neuroinflammation [ 13,18 ]. Mayo et al. found that CCL2 from...

.... Cerebral microvessels Blood-brain barrier Neuroinflammation Lipopolysaccharide p-glycoprotein Cytokine receptor IL15 TNF National Institutes of Health (NIH) 10.13039/100000002 Cellular Physiology and Biochemistry Original Paper Cell Physiol Biochem 2010;25:623-630 Accepted: March 12...

..., in neuroinflammation in Alzheimer’s disease. Alzheimer�s disease Amyloid peptide Microglia TLR4 CD14 TLR2 Neuroinflammation 30 10 2007 © 2007 S. Karger AG, Basel 2007 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated...