... susceptibility to apoptosis. Both, decreased SOCE and enhanced apoptosis of ChAc fibroblasts can be reversed by lithium treatment. [email protected] 9 05 2017 20 05 2017 11 8 2017 Calcium SOCE Lithium Apoptosis Neurodegeneration Orai1 Cell membrane scrambling...

... plaques in the AD brain [ 23 ]. Here we give an overview on experimental data that argue in favour of S1P as a potential molecular link connecting impaired lipid metabolism and neurodegeneration. Fig. 1 Scheme of sphingolipid metabolism. Ceramide is formed either de novo starting from...

.... Osmolyte transporter Neurodegeneration Kinase Electrophysiology The Tau tubulin Kinase 2 (TTBK2), a serine/threonine kinase [ 1 ] expressed in various tissues including the brain [ 2,3,4 ], heart [ 5 ], kidney [ 5 ], intestine [ 5 ] and tumor cells [ 6 ], contributes to the maintenance of neuron...

.... Alzheimer’s disease Retinopathy Neurodegeneration Neurovascular unit Polycystic kidney disease Cellular Physiology Cell Physiol Biochem 2012;30:1436-1443 and Biochemistry DOI: 10.1159/000343331 Published online: November 22, 2012 © 2012 S. Karger AG, Basel www.karger.com/cpb ABuccscehp/tWedu...

... and vasoregression both in the clinic and in animal models. A mild neurodegeneration with loss of ganglion cells is also described in the diabetic retina. Like VEGF-A, Epo is angioprotective and, in high doses, neuroprotective, however, without affecting vessel permeability. This study was to investigate the effect...