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Keywords: NLRP3 inflammasome
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Cellular Physiology and Biochemistry (2018) 47 (2): 523–534.
Published Online: 23 May 2018
..., and the histopathology of liver tissues was assessed. The expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and its target genes was examined using PCR. The activation of nuclear factor kappa-B (NF-κB) and the levels of inflammatory cytokines were determined. NLRP3 inflammasome and its components were...
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Cellular Physiology and Biochemistry (2018) 44 (6): 2269–2280.
Published Online: 14 December 2017
... cells (VSMCs) is a major initiating factor for vascular remodeling. The present study was designed to determine the roles of NLRP3 inflammasome activation in Ang II-induced VSMC phenotypic transformation and vascular remodeling in hypertension. Methods: Primary VSMCs from the aorta of NLRP3 knockout...
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Cellular Physiology and Biochemistry (2017) 44 (2): 741–750.
Published Online: 23 November 2017
...Wei Ding; Tingyan Liu; Xiao Bi; Zhiling Zhang Background/Aims: Growing evidence suggests mitochondrial dysfunction (MtD) and the Nlrp3 inflammasome play critical roles in chronic kidney disease (CKD) progression. We previously reported that Aldosterone (Aldo)-induced renal injury in vitro...
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Cellular Physiology and Biochemistry (2017) 43 (1): 247–256.
Published Online: 30 August 2017
... Reactive Oxygen Species Detection Assay Kit. Results: Macrophages isolated from diabetic wounds exhibited a pro-inflammatory phenotype, including sustained NLRP3 inflammasome activity associated with IL-1β secretion. Our data showed that high glucose inhibited autophagy, induced ROS production...
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Cellular Physiology and Biochemistry (2017) 42 (3): 901–912.
Published Online: 26 June 2017
... recorded after the last OVA challenge. Nasal mucosa tissues and serum were collected. MiR-133b expression, serum OVA-specific immunoglobulin E (IgE) concentration, proinflammatory cytokines (TNF-α, IL-4, IL-5, IL-10 and IFN-γ) levels, and Nlrp3 inflammasome activation were measured by RT-PCR, ELISA...
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