... for analysis of NCKX. Results: TGFβ1 (60 ng/ml, 24 h) significantly increased the transcript levels of NCX1, NCKX1, NCKX2 and NCKX5. Moreover, TGFβ1 (60 ng/ml, 24 h) significantly increased the activity of both, NCX and NCKX. The effect of TGFβ1 on NCX and NCKX transcript levels and activity was significantly...

... (SOCE). [Ca 2+ ] i could be decreased by Ca 2+ extrusion via Na + /Ca 2+ exchange. Mechanisms accomplishing SOCE include the pore-forming ion channel unit Orai1 and its regulator STIM1, Na + /Ca 2+ exchanger isoforms include NCX1. In MCF-7 breast carcinoma cells Orai1 and NCX1 have previously been shown...

... (SOCE) accomplished by the pore-forming ion channel unit Orai1 and its regulator STIM1, as well as Ca 2+ extrusion by Na + /Ca 2+ exchanger NCX1. Kinases participating in the orchestration of cell proliferation include the Janus activated kinase JAK2. The present study explored the impact...

... NCX1 Cardiac contractility modulation (CCM) Cardiac resynchronization therapy (CRT) Cardiac contractile function Absolute refractory period Electric pacing Congestive heart failure Congestive heart failure (CHF) is a highly prevalent disease in western society characterized by severely...