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Keywords: Mito-Tempo
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Cellular Physiology and Biochemistry (2017) 44 (2): 741–750.
Published Online: 23 November 2017
... is directly caused by mitochondrial reactive oxygen species (mtROS)-mediated activation of the Nlrp3 inflammasome. Here we aimed to determine whether a mitochondria-targeted antioxidant (Mito-Tempo) could prevent Aldo-induced kidney damage in vivo . Methods: C57BL/6J mice were treated with Aldo and/or Mito...