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Cellular Physiology and Biochemistry (2018) 51 (4): 1815–1829.
Published Online: 30 November 2018
... Bacillus Calmette-Guérin (BCG) as a model for mycobacterial infection. For in vitro assays we isolated bone marrow-derived macrophages from Wildtype mice or Nsm2-heterozygous and investigated the role of Nsm2 for macrophage migration/clustering as well as the involvement of p38 mitogen-activated protein...
Fengying Sun, Ying Ni, Hong Zhu, Jian Fang, Hua Wang, Jinxuan Xia, Fangfang Ding, Hongxing Shen, Shihe Shao
Cellular Physiology and Biochemistry (2018) 51 (3): 1250–1263.
Published Online: 28 November 2018
... by bioinformatics analysis, western blotting and dual luciferase reporter gene assays. Western blotting and immunohistochemistry (IHC) assay were performed to detect the protein expression. Transwell assay was used to determine the cell migration ability. Results: MiR-29a-3p was up-regulated in H.pylori -positive...
Cellular Physiology and Biochemistry (2018) 51 (3): 1276–1286.
Published Online: 27 November 2018
... with metformin in this study. Western blot assay was performed to detect th level of Bcl-2, Bax and Caspase-3. Scratch wound assay, transwell assay and Millicell invasion assay were used to assay the invasion and migration of EC9706 and Eca109 cells. Nude mice tumor models were used to assay the growth and lung...
Michael Kittl, Heidemarie Dobias, Marlena Beyreis, Tobias Kiesslich, Christian Mayr, Martin Gaisberger, Markus Ritter, Hubert H. Kerschbaum, Martin Jakab
Cellular Physiology and Biochemistry (2018) 50 (4): 1460–1473.
Published Online: 25 October 2018
.... Similar to the expansion of the lamellipodium we assume that glycine also affects the migration of microglial cells in a cell volume-dependent manner. Methods: Mean cell volume (MCV) and cell migration were determined using flow cytometry and trans-well migration assays, respectively. Electrophysiological...
Ming-Ju Hsieh, Mei-Chung Chin, Chia-Chieh Lin, Yi-Ting His, Yu-Sheng Lo, Yi-Ching Chuang, Mu-Kuan Chen
Cellular Physiology and Biochemistry (2018) 50 (3): 911–923.
Published Online: 24 October 2018
... and the relevant signaling pathways underlying mechanisms of SCC-9 SAS and HSC-3 oral cancer cell lines by MTT assay Wound healing Transwell assay Zymography and western blot analysis. Results: Our findings indicated that PSH inhibits migration and invasion ability by reducing the protein activity and expression...
Cellular Physiology and Biochemistry (2018) 50 (3): 810–822.
Published Online: 23 October 2018
... the cell proliferation, migration/invasion, and apoptosis respectively. Results: Our study explored the expression profiles of KIF2A and miR-206 in the patients with ovarian cancer. We found that overexpression of KIF2A was associated with a poor prognosis in ovarian cancer. We also found that KIF2A mRNA...
Cellular Physiology and Biochemistry (2018) 49 (3): 1138–1150.
Published Online: 07 September 2018
... RNA against TGFBI (shTGFBI) on cell proliferation, migration, invasion and apoptosis. Western blot analysis was performed to examine the expression of proteins related to apoptosis and proteins in the PI3K/Akt signaling pathway. Results: High TGFBI expression was found to be associated with poor...
Cellular Physiology and Biochemistry (2018) 49 (3): 911–919.
Published Online: 05 September 2018
.... This study was aimed to investigate cytotoxic effect of external qi of Yan Xin Qigong (YXQ-EQ) toward human lung adenocarcinoma A549 cells as well as its effect on signaling pathways promoting migration, invasion and epithelial-to-mesenchymal transition (EMT) in A549 cells. Methods: Cytotoxic effect of YXQ...
Cellular Physiology and Biochemistry (2018) 49 (1): 217–225.
Published Online: 23 August 2018
...) in the development of esophageal cancer. Methods: The expression of RUNX2 in esophageal carcinoma tissues and cells was investigated by qRT-PCR. Effects of RUNX2 on cell viability, apoptosis, migration and invasion were assessed using MTT assay, flow cytometry assay/western blot analysis, and Transwell assays...
Cellular Physiology and Biochemistry (2018) 48 (4): 1694–1702.
Published Online: 03 August 2018
... receptor potential canonical 3 (TRPC3) expression have poor survival rates. The aim of this study is to evaluate the effects of Ethyl-1-(4-(2,3,3-trichloroacrylamide)phenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (Pyr3), a selective TRPC3 channel blocker, on the proliferation and migration of human...
Yongze Liu, Han Zhou, Xiaofeng Ma, Chuanyao Lin, Ling Lu, Dingding Liu, Dengbin Ma, Xia Gao, Xiao Yun Qian
Cellular Physiology and Biochemistry (2018) 48 (4): 1556–1562.
Published Online: 02 August 2018
... was used to examine cell proliferative ability. Flow cytometry was used to examine cell cycle distribution, the scratch test was employed to examine cell migration, and Transwell migration assay (Boyden chamber) was used to study cell invasion. Results: The optimal concentrations of prodigiosin and 5-FU...
Yieun Jung, So-Hee Ahn, Hyunju Park, Sang Hui Park, Kyungsun Choi, Chulhee Choi, Jihee Lee Kang, Youn-Hee Choi
Cellular Physiology and Biochemistry (2018) 48 (3): 1332–1346.
Published Online: 26 July 2018
... cells (NCs) on microglia infiltration in GBM and the tumor-infiltrating microglia-induced factors in GBMs. Methods: In this study, to address whether necrosis or necrosis-exposed GBM cells affect the degree of microglia/macrophage infiltration, migration and invasion/infiltration assays were performed...
Yanqin Zhang, Qianghua Hu, Guixin Li, Lili Li, Shoulei Liang, Yun Zhang, Jiayong Liu, Zhengfu Fan, Lin Li, Bingzheng Zhou, Yongxin Ruan, Xueli Yang, She’an Chen, Tianyang Mu, Guowen Wang, Shunbin Xiong
Cellular Physiology and Biochemistry (2018) 48 (3): 1099–1111.
Published Online: 24 July 2018
.../+ mouse metastatic osteosarcomas. Accordingly, we investigated the role of ONZIN in human osteosarcoma metastasis. Methods: ONZIN function and its downstream targets were examined in osteosarcoma cell lines. Assays related to tumorigenesis and metastasis, including cell migration, invasion, clonogenic...
Cellular Physiology and Biochemistry (2018) 47 (5): 1871–1882.
Published Online: 29 June 2018
... to investigate the effects of VB on glioblastoma cell proliferation, apoptosis, migration, and invasion as well as the mechanism involving signal transducer and activator of transcription 3 (STAT3) and Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP-1). Methods: U87 cells were assigned...
Fengming Yang, Ke Wei, Zhiqiang Qin, Weitao Liu, Chuchu Shao, Chaoshan Wang, Ling Ma, Mengyan Xie, Yongqian Shu, Hua Shen
Cellular Physiology and Biochemistry (2018) 47 (1): 245–256.
Published Online: 11 May 2018
... on invasion and migration was determined in vitro using transwell and wound-healing assays. The molecular mechanism underlying the relevance between miR-598 and DERL1 was elucidated by luciferase assay and Western blot. Western blot assessed the expression levels of EMT hallmark genes in cell lines. Xenograft...
Nana Wei, Zhibing Lin, Zhengmao Xu, Jie Cao, Yongzhi Zhou, Houshuang Zhang, Haiyan Gong, Jinlin Zhou, Guoqing Li
Cellular Physiology and Biochemistry (2018) 46 (6): 2385–2400.
Published Online: 08 May 2018
.... Methods: Different tumor cells were treated with RHcyst-1 in vitro . Proliferation activity was evaluated using Cell Counting Kit-8, and migration and invasion were determined by wound healing and Transwell® invasion assays. In addition, a mouse tumor therapy model was established by inoculating the left...
Ying Xu, Guohua Zhang, Chen Zou, Heng Zhang, Zhigang Gong, Weixin Wang, Gui Ma, Pengcheng Jiang, Wenbo Zhang
Cellular Physiology and Biochemistry (2018) 46 (6): 2445–2459.
Published Online: 05 May 2018
... assay and wound healing assay were used to evaluate the proliferation, invasion and migration of GC cells, respectively. Bioinformatics analysis and luciferase reporter assay were performed to disclose the interaction between MT1JP, miR-214-3p and RUNX3. Western blot and immunofluorescence were applied...
Xiaobing Liu, Dangling Zhang, Yaxing Hao, Qian Liu, Yuqi Wu, Xin Liu, Jing Luo, Tao Zhou, Bishao Sun, Xing Luo, Jie Xu, Qingqing Wang, Zhenxing Yang, Longkun Li
Cellular Physiology and Biochemistry (2018) 46 (6): 2517–2531.
Published Online: 05 May 2018
... is known about its effects on renal cell carcinoma (RCC) tumorigenesis. This study, therefore, investigated the effects of cyanidin on the proliferation, migration, and invasion of renal cell carcinoma lines and demonstrated, for the first time, significant inhibitory effects of cyanidin on RCC...
Ji Young Oh, Gee Euhn Choi, Hyun Jik Lee, Young Hyun Jung, So Hee Ko, Chang Woo Chae, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Chang-Kyu Lee, Ho Jae Han
Cellular Physiology and Biochemistry (2018) 46 (5): 1749–1767.
Published Online: 25 April 2018
... contributes to the precise molecular mechanisms responsible for stem cell migration. Thus, we investigate the effect of glucose on the regulation of the human umbilical cord blood-derived mesenchymal stem cell (hUCB-MSC) migration, and analyze the mechanism accompanied by this effect. Methods: Western blot...
Cellular Physiology and Biochemistry (2018) 46 (3): 1286–1304.
Published Online: 16 April 2018
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2018 Breast cancer MicroRNA-34a CXCL10 TLR signaling pathway Migration Invasion Cellular Physiology Cell Physiol Biochem 2018;46:1286-1304 and Biochemistry DOOII...