...Cheng Zhang; Yu Liang; Ming-Hui Ma; Kun-Zhe Wu; Chun-Dong Zhang; Dong-Qiu Dai Background/Aims: MicroRNAs have a significant role in the tumorigenesis and progression of cancers, including gastric cancer (GC). Our study aimed to identify a novel biomarker to predict the prognosis of patients with GC...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Intrahepatic cholestasis of pregnancy MicroRNA Noninvasive biomarker Microarray Intrahepatic cholestasis...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Epilepsy TLE Circular RNA microRNA Sponge Epilepsy...

... fibrosis Hepatic stellate cell Thymosin β4 Circular RNA MicroRNA CeRNA Progression of liver fibrosis commonly occurs in virtually all types of chronic liver diseases (CLDs) [ 1 ]. During liver fibrosis, several complex processes occur, including excessive accumulation and hyperplasia...

... with E. granulosus . Microarray analysis of miRNAs showed that 28 miRNAs were differentially expressed in M-MDSCs from the two experimental mice groups, and 272 target genes were predicted using the microRNA databases TargetScan, PITA and microRNAorg. These target genes were mainly involved...

... microRNAs (miRNAs) and the corresponding targeting genes involved in the pathology of GDM still remain to be elucidated. We aimed to identify the dysregulated miRNAs and the corresponding mRNA targets through an integrated miRNA and mRNA transcriptomic profiles analysis and investigate the role...

...Zhaoxia Hu; Peipei Wang; Jiaxin Lin; Xingrong Zheng; Fangji Yang; Genglin Zhang; Dabiao Chen; Junqiang Xie; Zhiliang Gao; Liang Peng; Chan Xie Background/Aims: MicroRNA-197 (miR-197) has been shown to play roles in epithelialmesenchymal transition (EMT) and metastasis. The Wnt/β-catenin pathway...

...Meng Qiao; Jian Ding; Jianjun Yan; Ronghua Li; Jian Jiao; Qing Sun Background/Aims: Circular RNAs (circRNAs) are evolutionary conserved circular non-coding RNAs that play a role in several diseases by sequestering (sponging) microRNAs (miRNAs). However, their role in psoriasis remains unclear...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Glioblastoma Invasion MicroRNA NTSR1 SOCS6 NTSR1 stimulation triggers the activation of various intracellular signaling pathways, including extracellular signal...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Total flavonoid Renal fibrosis MicroRNA Signaling pathway Carya cathayensis , family Juglandaceae, is widely distributed around...

... for metastatic SMM are lacking. Methods: Laser-capture microdissection combined with microRNA microarray and RT-qPCR was performed in formalin-fixed paraffin-embedded tissue samples from SMM patients whose follow-up studies were carried out in parallel. In vitro cell proliferation and invasion assays, gelatin...

...Zhigang Zhang; Bing Pan; Shaocheng Lv; Zhiwei Ji; Qian Wu; Ren Lang; Qiang He; Xin Zhao Background/Aims: MicroRNAs (miRNAs) are promising biomarkers for pancreatic cancer (PaCa). However, systemic and unified evaluations of the diagnostic value of miRNAs are lacking. Therefore, we performed...

... a critical role in the initiation and progression of CCH. However, the underlying mechanisms remain unclear. In this study, we identified the effect of a microRNA (miR) on autophagy under CCH. Methods: A CCH rat model was established by two-vessel occlusion (2VO). Learning and memory abilities were assessed...

... and developmental mechanisms for both types of HCC through differentially expressed microRNAs (miRNAs) using bioinformatic analysis. Methods: The miRNA-seq data and clinical data of patients (from The Cancer Genome Atlas (TCGA) database) were utilized to determine differentially expressed miRNAs between cirrhotic...

...Hongmei Lang; Yang Xiang; Ning Lin; Zhihua Ai; Zhiqing You; Jie Xiao; Dan Liu; Yongjian Yang Background/Aims: MicroRNAs (miRNAs) are a novel class of small RNAs that participate in a variety of biological processes. Although miRNAs have been linked to insulin synthesis and glucose homeostasis...

...Yuanyuan Mi; Kewei Ren; Jiangang Zou; Yu Bai; Lifeng Zhang; Li Zuo; Atsushi Okada; Takahiro Yasui Background/Aims: MicroRNAs (miRNAs) are a class of small non-coding RNA molecules which play a significant role in transcriptional and translational regulation. Published data on the association...

... new insights into the mechanisms of interactions between HSV-1 and the host. [email protected] Circular RNA MicroRNA Gene HSV-1 KMB17 Whole transcriptome 4 01 2018 4 05 2018 4 7 2018 © 2018 The Author(s). Published by S. Karger AG, Basel 2018 Open Access...

... of circRNAs for PTC. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were employed to determine the biological functions of differentially expressed circRNAs. Bioinformatic analyses were applied to predict interactions between circRNAs and microRNAs (miRNAs...

...Dongsheng Wang; Si Si; Qiang Wang; Guangcheng Luo; Qin Du; Qi Liang; Xiaolan Guo; Guoyuan Zhang; Jiafu Feng; Zhengwei Leng Background/Aims: MicroRNAs (miRNAs) play a crucial role in erythropoiesis. MiR-23a∼27a∼24-2 clusters have been proven to take part in erythropoiesis via some proteins. CDC25B...

...Yuanyuan Zhou; Xia Zheng; Jiaojiao Lu; Wei Chen; Xu Li; Le Zhao Background/Aims: The Warburg effect is one of the main energy metabolism features supporting cancer cell growth. 20(S)-Rg3 exerts anti-tumor effect on ovarian cancer partly by inhibiting the Warburg effect. microRNAs are important...