... of villin 1, a differentially expressed protein (DEP) in mouse mesangial cells, was investigated. Results: Persistent mesangiolysis and focal hypercellularity together with reduced activation of cell proliferation in the HabuU model induced more serious renal injury compared with that in the Habu model...

... for podocyte damage. This study hypothesized that conditioned mesangial medium may induced EMT process of podocytes and thereby lead to glomerular injury or sclerosis. Materials and Methods: Podocytes were incubated in medium from mesangial cells incubated with aggregated IgA1(aIgA1) isolated from IgAN...

...) antagonizes the transcription factor Myc and is believed to be a tumor suppressor. However, no studies have investigated its effect on mesangial cell proliferation. Methods: To investigate the effect of Mxi1 on renal mesangial cell proliferation, we established a classic rat anti-Thy1 mesangial proliferative...

...Masashi Nishida; Hidekazu Kawakatsu; Hiroshi Komatsu; Kohhei Ishiwari; Megumi Tamai; Tadashi Sawada; Takeshi Hasegawa; Hiroyasu Nishikawa Aqueous solutions containing extracts of cultured rat mesangial cells treated with and without arginine vasopressin (AVP) were measured by phosphorus-31 nuclear...

...Joseph Mattana; Pravin C. Singhal Proliferation of mesangial cells (MC) is regarded as a precursor to the development of glomerulosclerosis and may be mediated by mitogenic vasoconstrictors such as angiotensin II (ANG-II) and endothelin 1 (ET-1). Dietary supplementation with the nitric oxide...