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Keywords: Macrophage
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Cellular Physiology and Biochemistry (2018) 47 (3): 1133–1140.
Published Online: 15 June 2018
... and the cell sources in ALF. Methods: Human monocytic leukemia line U937 cells were treated with 12- O -tetradecanoylphorbol-l3-acetate (PMA) (100 ng/ mL) for 24 h to induce activated macrophages. In the presence of lipopolysaccharide (LPS, 1 μg/mL), activated macrophages and human hepatocyte line L02 cells...
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Cellular Physiology and Biochemistry (2018) 45 (4): 1434–1443.
Published Online: 16 February 2018
... the metabolic characteristics of the mice. Compared to the control group, knockout of the 18-kDa FGF-2 isoform significantly attenuated atherogenesis, reduced aortic plaques, reduced macrophage infiltration and suppressed oxidative stress in mice fed with a high fat diet at all-time points. Conclusions: 18-kDa...
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Cellular Physiology and Biochemistry (2017) 41 (4): 1457–1467.
Published Online: 17 March 2017
...Peng Tang; Chunguang Duan; Zheng Wang; ChunMei Wang; Guolin Meng; Kaifeng Lin; Qian Yang; Zhi Yuan Aim: The aims of this study are to investigate the effects of neurotransmitters NPY and CGRP on ERK signaling in fracture healing, and to identify the correlation between macrophage aggregation...
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Cellular Physiology and Biochemistry (2017) 41 (1): 274–285.
Published Online: 30 January 2017
... in the regulation of TLR4-associated immune responses in the macrophage cell line of RAW264.7. Methods: Nogo-B was up- and down-regulated through the use of appropriate adenoviral vectors or siRNA, and the effects of Nogo-B on macrophages under liposaccharide (LPS) stimulation were evaluated via western blotting...
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Cellular Physiology and Biochemistry (2016) 40 (6): 1538–1548.
Published Online: 21 December 2016
... in fibrogenesis. However, the relationship between inflammatory macrophages and PMCs remains elusive. In this study, we investigated the effects of different polarized macrophages on EMT of HMrSV5 PMCs. Methods: Monocytes were polarized to M1/M2 macrophages before being added to HMrSV5 in direct or indirect...
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Cellular Physiology and Biochemistry (2016) 38 (1): 415–426.
Published Online: 29 January 2016
...Yonggang Yao; Di Yang; Yu Han; Wei Wang; Na Wang; Jian Yang; Chunyu Zeng Background/Aims: Oxidized low-density lipoprotein (Ox-LDL) induces macrophage proliferation, a key physiological process which leads to atherosclerosis. The aim of this study was to determine the effects of dopamine D 1 -like...
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Cellular Physiology and Biochemistry (2015) 36 (5): 2012–2024.
Published Online: 17 July 2015
... experiments, we sought to determine if inflammasome activators can induce IL-1β processing and secretion in THP-1 cells. For this current study, THP-1 cells were selected because of their similarity to the activated alveolar macrophages present in bronchoalveolar lavage (BAL) fluid [ 21 ]. In addition...
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Cellular Physiology and Biochemistry (2015) 36 (5): 2025–2038.
Published Online: 17 July 2015
... expression and activity were induced by LPS in RAW264.7 cells, and examined by real-time PCR, western blotting and gelatin zymography, respectively. ELISA was used to determine the changes in MMP-9 secretion among the groups. Macrophage migration was evaluated using transwell migration assay. Knockdown of a7...