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Keywords: Macrophage
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Journal Articles
Subject Area:
Further Areas
Liang Li, Wei Wei, Zhenzhen Li, Haiyan Chen, Yu Li, Wei Jiang, Weisan Chen, Guangyao Kong, Jun Yang, Zongfang Li
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (2): 557–574.
Published Online: 20 November 2018
...Liang Li; Wei Wei; Zhenzhen Li; Haiyan Chen; Yu Li; Wei Jiang; Weisan Chen; Guangyao Kong; Jun Yang; Zongfang Li Background/Aims: Liver fibrosis is a complex process of tissue remodeling in response to injury. Hepatic macrophages have been identified as a key player in this process. As the largest...
Journal Articles
Subject Area:
Further Areas
Xiao-Zhi Bai, Ju-Lei Zhang, Yang Liu, Wei Zhang, Xiao-Qiang Li, Ke-Jia Wang, Meng-Yuan Cao, Jia-Ning Zhang, Fu Han, Ji-Hong Shi, Da-Hai Hu
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (2): 489–500.
Published Online: 29 August 2018
.... The inflammatory response of macrophages is critical during sepsis. Methods: Macrophages were stimulated with LPS. Western blotting and qRT-PCR were used to detect inflammatory responses. Then, the inhibitor of microRNA-138 was transfected and Western blotting, qRT-PCR, H&E staining and ELISA were used...
Journal Articles
Subject Area:
Further Areas
Yujuan Zhou, Longzheng Xia, Qiang Liu, Heran Wang, Jingguan Lin, Linda Oyang, Xiaoyan Chen, Xia Luo, Shiming Tan, Yutong Tian, Min Su, Ying Wang, Pan Chen, Yang Wu, Hui Wang, Qianjin Liao
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 47 (4): 1399–1410.
Published Online: 19 June 2018
... cancer (GC). However, the role and relationship of activated macrophages with gastric mucous epithelium cells in initiating and maintaining the inflammatory process during gastric carcinogenesis remains unclear. Methods: The tumour associated macrophages (TAMs) density of gastric cancer was characterized...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 47 (3): 1133–1140.
Published Online: 15 June 2018
... and the cell sources in ALF. Methods: Human monocytic leukemia line U937 cells were treated with 12- O -tetradecanoylphorbol-l3-acetate (PMA) (100 ng/ mL) for 24 h to induce activated macrophages. In the presence of lipopolysaccharide (LPS, 1 μg/mL), activated macrophages and human hepatocyte line L02 cells...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 45 (4): 1434–1443.
Published Online: 16 February 2018
... the metabolic characteristics of the mice. Compared to the control group, knockout of the 18-kDa FGF-2 isoform significantly attenuated atherogenesis, reduced aortic plaques, reduced macrophage infiltration and suppressed oxidative stress in mice fed with a high fat diet at all-time points. Conclusions: 18-kDa...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 45 (1): 332–342.
Published Online: 19 January 2018
...: ARDS rat model was established by lipopolysaccharide, with compromised gas exchange capacity and lung edema. The inflammatory cells from bronchoalveolar lavage fluid (BALF) were profiled with automatic blood cell analyzer. The relative fluorescence intensity of BALF-derived macrophages was analyzed...
Journal Articles
Subject Area:
Further Areas
Ning Wang, Jian Gao, Min Jia, Xue Ma, Zhanxiang Lei, Fei Da, Fei Yan, Huinan Zhang, Ying Zhou, Mingkai Li, Gonghao He, Jingru Meng, Xiaoxing Luo
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 44 (5): 1696–1714.
Published Online: 06 December 2017
... receptor agonist Exendin-4 is beneficial for osteoblast differentiation and increases the number of osteoblasts. Methods: We constructed an ovariectomized model to evaluate the impact of Exendin-4 on bone formation in osteoporosis. A macrophage-depleted model was also created to investigate the effect...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (5): 2093–2104.
Published Online: 15 August 2017
... by macrophages from diabetic C57BL/6 mice stimulated with lipopolysaccharides (LPS). Methods: Bone marrow-derived macrophages (BMDM) and tissue-specific macrophages from diabetic (alloxan 60 mg/kg, i.v.) male C57BL/6 mice were stimulated by LPS (100 ng/mL) and/or treated by insulin (1 mU/mL). Results: Using BMDM...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (2): 495–505.
Published Online: 05 June 2017
... on atherosclerosis (AS). We aim to study their potential function in AS. Methods: An oxidized low-density lipoprotein (ox-LDL) induced AS model constructed with PTPRO over-expressing RAW264.7 cells and PTPRO knockout macrophages. Cell apoptosis was assayed by flow cytometry and fatty accumulation was evaluated...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (1): 91–102.
Published Online: 11 May 2017
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2017 MicroRNA-21 Bacilli Calmette-Guerin Toll-like receptors 4 Myeloid differentiation factor 88 Signaling pathway Macrophage Cellular Physiology Cell Physiol...
Journal Articles
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Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (6): 2432–2446.
Published Online: 03 May 2017
... was established using ApoE -/- mice fed a western diet. En face Oil Red O staining was used to measure atherosclerotic plaque size. Hematoxylin and eosin staining and immunohistochemical staining were used to observe plaque morphology and assess the location of macrophages and heme oxygenase 1 (HO-1). HO-1 mRNA...
Journal Articles
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Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (4): 1457–1467.
Published Online: 17 March 2017
...Peng Tang; Chunguang Duan; Zheng Wang; ChunMei Wang; Guolin Meng; Kaifeng Lin; Qian Yang; Zhi Yuan Aim: The aims of this study are to investigate the effects of neurotransmitters NPY and CGRP on ERK signaling in fracture healing, and to identify the correlation between macrophage aggregation...
Journal Articles
Subject Area:
Further Areas
Lei Tian, Xinghua Shao, Yuanyuan Xie, Qin Wang, Xiajing Che, Minfang Zhang, Weijia Xu, Yao Xu, Shan Mou, Zhaohui Ni
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (2): 769–783.
Published Online: 13 February 2017
..., KIM-1 expression was significantly increased during the early stage of kidney injury and was persistently elevated in renal fibrosis. Our immunofluorescence staining results indicated that KIM-1-positive tubules were surrounded by macrophage infiltrates in regions of kidney injury. Moreover, our...
Journal Articles
Subject Area:
Further Areas
Ying Zhu, Qiang Tong, Jia Ye, Yunye Ning, Ye Xiong, Meng Yang, Hua Xiao, Jian Lu, Wujian Xu, Jiandong Li, Qiang Li
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (1): 274–285.
Published Online: 30 January 2017
... in the regulation of TLR4-associated immune responses in the macrophage cell line of RAW264.7. Methods: Nogo-B was up- and down-regulated through the use of appropriate adenoviral vectors or siRNA, and the effects of Nogo-B on macrophages under liposaccharide (LPS) stimulation were evaluated via western blotting...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 40 (6): 1538–1548.
Published Online: 21 December 2016
... in fibrogenesis. However, the relationship between inflammatory macrophages and PMCs remains elusive. In this study, we investigated the effects of different polarized macrophages on EMT of HMrSV5 PMCs. Methods: Monocytes were polarized to M1/M2 macrophages before being added to HMrSV5 in direct or indirect...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 40 (3-4): 486–498.
Published Online: 25 November 2016
...Yuanqin Yin; Fei Li; Jing Shi; Songlin Li; Jingjing Cai; Youhong Jiang Background/Aims: The primary objective of this study was to investigate the role of miR-146a in inducing the inflammatory infiltration of macrophages in polymyositis/dermatomyositis (PM/DM) through targeting TNF receptor...
Journal Articles
Subject Area:
Further Areas
Wenting Ma, Le Tao, Xuefei Wang, Qinyi Liu, Wei Zhang, Qiuying Li, Chunfeng He, Dongying Xue, Jie Zhang, Cheng Liu
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 39 (5): 1837–1849.
Published Online: 17 October 2016
... or sorafenib treatment. The expression of CD68, a macrophage marker, and the pro-inflammatory cytokines, MCP1 and CXCR3, were immunohistochemically analyzed. The involvement of macrophages in the formation of renal fibrosis was studied using confocal microscopy. Results: Renal histopathology improved...
Journal Articles
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 38 (1): 415–426.
Published Online: 29 January 2016
...Yonggang Yao; Di Yang; Yu Han; Wei Wang; Na Wang; Jian Yang; Chunyu Zeng Background/Aims: Oxidized low-density lipoprotein (Ox-LDL) induces macrophage proliferation, a key physiological process which leads to atherosclerosis. The aim of this study was to determine the effects of dopamine D 1 -like...
Journal Articles
Subject Area:
Further Areas
Rajanbabu Venugopal, Lakshmi Galam, Ruan Cox, Jutaro Fukumoto, Young Cho, Prasanna Tamarapu Parthasarathy, Richard F. Lockey, Narasaiah Kolliputi
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 36 (5): 2012–2024.
Published Online: 17 July 2015
... experiments, we sought to determine if inflammasome activators can induce IL-1β processing and secretion in THP-1 cells. For this current study, THP-1 cells were selected because of their similarity to the activated alveolar macrophages present in bronchoalveolar lavage (BAL) fluid [ 21 ]. In addition...
Journal Articles
Subject Area:
Further Areas
Yong-Hua Yang, Dong-Ling Li, Xue-Yuan Bi, Lei Sun, Xiao-Jiang Yu, Huan-Le Fang, Yi Miao, Ming Zhao, Xi He, Jin-Jun Liu, Wei-Jin Zang
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 36 (5): 2025–2038.
Published Online: 17 July 2015
... expression and activity were induced by LPS in RAW264.7 cells, and examined by real-time PCR, western blotting and gelatin zymography, respectively. ELISA was used to determine the changes in MMP-9 secretion among the groups. Macrophage migration was evaluated using transwell migration assay. Knockdown of a7...
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