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Keywords: MC3T3-E1
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Journal Articles

Use of an Osteoblast Overload Damage Model to Probe the Effect of Icariin on the Proliferation, Differentiation and Mineralization of MC3T3-E1 Cells through the Wnt/β-Catenin Signalling Pathway

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Yingjie Liu, Lulu Huang, Baohui Hao, Hao Li, Shuanglong Zhu, Qiangsong Wang, Ruixin Li, Yunqiang Xu, Xizheng Zhang
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 41 (4): 1605–1615.
https://doi.org/10.1159/000470896
Published Online: 28 March 2017
.... Methods: Mouse MC3T3-E1 cells were exposed to mechanical tensile strain using a four- point bending device to create an overload damage model. An MTT assay was performed to determine the effects of icariin on MC3T3-E1 cell proliferation. The mRNA and protein levels of ALP, COL-I, OCN, RUNX2 and β-catenin...
View article titled, Use of an Osteoblast Overload Damage Model to Probe the Effect of Icariin on the Proliferation, Differentiation and Mineralization of <span class="search-highlight">MC3T3</span>-<span class="search-highlight">E1</span> Cells through the Wnt&#x2F;β-Catenin Signalling Pathway
Open the PDF for Use of an Osteoblast Overload Damage Model to Probe the Effect of Icariin on the Proliferation, Differentiation and Mineralization of <span class="search-highlight">MC3T3</span>-<span class="search-highlight">E1</span> Cells through the Wnt/β-Catenin Signalling Pathway in another window
Journal Articles

Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth

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Joseph Caverzasio, Cyril Thouverey
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2011) 27 (3-4): 243–250.
https://doi.org/10.1159/000327950
Published Online: 01 April 2011
... including activation of the calcium sensing receptor (CaSR) and a yet undefined mechanism. In the present study, we investigated the CaSR-independent molecular mechanism by which SrRan stimulates osteoblast growth. Methods: MC3T3-E1 and primary osteoblastic cells, specific inhibitors of receptor tyrosine...
View article titled, Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth
Open the PDF for Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth in another window