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Keywords: MAPKs
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Cellular Physiology and Biochemistry (2018) 46 (4): 1628–1642.
Published Online: 20 April 2018
...-κBp65, p53, Bax and PCNA were detected by Immunohistochemistry. To gain an insight into the molecular signaling mechanisms, we determined the effect of CM on MAPKs, NF-κB and PI3K/Akt/eNOS pathways by Western blotting. Results: CM lowered 5-FU-triggered increase of creatinine, BUN, Kim-1 and NGAL renal...
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Cellular Physiology and Biochemistry (2018) 46 (3): 907–924.
Published Online: 13 April 2018
... in the progression of GC, and its mechanism may be related to the regulation of integrin family proteins, which leads to the sequential regulation of the PI3K/AKT, MAPK/ERK and MAPK/p38 pathways. Gastric cancer (GC) is a gastrointestinal malignancy originating from the epithelium and is one of the most common...
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Cellular Physiology and Biochemistry (2017) 42 (6): 2559–2568.
Published Online: 23 August 2017
... RAW 264.7 and the anti-inflammatory efficacy of the antioxidant alpha-lipoic acid (ALA). Methods: ELISA and western blotting analyses were conducted to detect the release of TNF-α from histone-stimulated RAW 264.7 macrophages and the associated phospho-activation of MAPKs (ERK and p38) and NF-κB p65...
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Cellular Physiology and Biochemistry (2015) 35 (4): 1454–1466.
Published Online: 12 March 2015
... for 12 h (normal plasma; Cytomix; TNF-α; IL-1β; IFN-γ; trauma plasma; anti-TNF-α antibody; SB203580). Myocyte apoptosis, cytokine levels, and MAPKs activation, as the primary experimental outcomes, were measured by TUNEL, flow cytometry, ELISA and Western blot, respectively. Results: Myocyte apoptosis...
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Cellular Physiology and Biochemistry (2014) 33 (2): 357–364.
Published Online: 06 February 2014
.... Moreover, genipin could suppress nuclear factor kappa B (NF-κB) p65, extracellular signalregulated kinase (ERK) and MAPK/ERK kinase (MEK) phosphorylations in IL-1ß-stimulated HPDLCs. NF-κB inhibitor and ERK inhibitor significantly inhibited IL-6 and CCL20 productions from IL-1ß-stimulated HPDLCs...
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Cellular Physiology and Biochemistry (2009) 23 (1-3): 053–064.
Published Online: 18 February 2009
... intracellular Ca 2+ levels via regulation of phospholipase C (PLC) and activated protein kinase C (PKC). LA activated phosphatidylinositol 3-kinase (PI3K)/Akt and p44/42 mitogen-activated protein kinases (MAPKs). U73122 (PLC inhibitor), staurosporine (PKC inhibitor), LY294002 (PI3K inhibitor), and Akt inhibitor...
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Cellular Physiology and Biochemistry (2008) 22 (5-6): 715–724.
Published Online: 09 December 2008
... MAPKs PKA PKC Sugar Cellular Physiology and Biochemistry Original Paper Cell Physiol Biochem 2008;22:715-724 Accepted: September 02, 2008 Lipopolysaccharide Induces Inhibition of Galactose Intestinal Transport in Rabbits in vitro Pilar Amador1, M. Carmen Marca2,5, Josefina García-Herrera1, M...