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Keywords: Lung cancer
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Cellular Physiology and Biochemistry (2018) 51 (1): 1–10.
Published Online: 15 November 2018
...Yuan Qiao; Jingtao Chen; Chao Ma; Yingmin Liu; Peitong Li; Yalin Wang; Lin Hou; Ziling Liu Background/Aims: Lung cancer is the leading cause of cancer-related deaths worldwide. The outcome of patients with non-small cell lung cancer remains poor; the 5-year survival rate for stage IV non-small cell...
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Cellular Physiology and Biochemistry (2018) 50 (2): 721–733.
Published Online: 11 October 2018
...Jinhua Lu; Yazhen Zhong; Jian Chen; Xianlei Lin; Zechen Lin; Nan Wang; Shengyou Lin Background/Aims: Radiotherapy plays a critical role in lung cancer treatment. Radiation can activate transforming growth factor-β (TGF-β) signaling and induce the epithelial-mesenchymal transition (EMT), which may...
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Cellular Physiology and Biochemistry (2018) 49 (1): 235–244.
Published Online: 23 August 2018
... furanocoumarin compound, on γδ T cell-mediated cytotoxicity against CD133 + lung cancer cells. Methods: CD133 + and CD133 - subgroups from A549 and PC9 lung cancer cells were sorted by using flow cytometry. The cytotoxicity of γδ T cells against cancer cells was evaluated by measuring lactate dehydrogenase...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1703–1709.
Published Online: 03 August 2018
...Peng-Fei Li; Qi-Gang Zhang Background/Aims: The E3 ubiquitin ligase ITCH plays an important role in invasive and metastatic cancers. However, the role of ITCH in the progression of lung cancer has not been fully described. Methods: Real-time PCR was used to detect the expression of ITCH mRNA...
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Cellular Physiology and Biochemistry (2018) 46 (4): 1595–1605.
Published Online: 20 April 2018
... with a higher NLR and PLR (p< 0.001). The NLR and PLR were sustained in patients who obtained a CR compared with moderate or poor response patients. The lower NLR of pretreatment was independently associated with a favourable prognosis in whole patients with lung cancer (HR: 0.69, 95% CI, 0.55-0.85, p...
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Cellular Physiology and Biochemistry (2018) 45 (5): 2095–2106.
Published Online: 07 March 2018
... with structurally modified SIO (CSIO, 5 µM) significantly inhibited cell proliferation and induced apoptosis in lung cancer cell line A549. The mitochondrial pathway, death receptor pathway and ER stress induced apoptosis were stimulated upon CSIO treatment. The administration with respective inhibitors including...
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Cellular Physiology and Biochemistry (2018) 45 (3): 1270–1283.
Published Online: 09 February 2018
...Seong-Min Park; Eun-Young Choi; Dong-Hyuck Bae; Hyun Ahm Sohn; Seon-Young Kim; Youn-Jae Kim Background/Aims: Recent studies have revealed that many long non-coding RNAs (lncRNAs) play oncogenic or tumor-suppressive roles in various cancers. Lung cancer is the leading cause of cancer-related death...
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Cellular Physiology and Biochemistry (2018) 44 (6): 2138–2146.
Published Online: 12 December 2017
...Jiangmin Zhao; Le Li; Qian Wang; Hongxiu Han; Qing Zhan; Ming Xu Background/Aims: Lung adenocarcinoma, a form of non-small cell lung cancer with high lethality at an advanced stage, is becoming more common in women, non- or never-smokers, and even young adults. At present, there are still...
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Cellular Physiology and Biochemistry (2017) 44 (4): 1425–1434.
Published Online: 30 November 2017
...Mengmeng Dou; Keyan Zhu; Zhirui Fan; Yuxuan Zhang; Xiufang Chen; Xueliang Zhou; Xianfei Ding; Lifeng Li; Zhaosen Gu; Maofeng Guo; Ming Yan; Xiaoming Deng; Peihong Shen; Shuling Wang Background/Aims: In contrast to men, women have experienced a rapid increase in lung cancer mortality. Numerous...
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Cellular Physiology and Biochemistry (2017) 44 (2): 467–478.
Published Online: 15 November 2017
... (CRC), medulloblastoma (MDB), and ovarian cancer. Nevertheless, little is known about its function in lung cancers. Methods: We first knocked down β-catenin by siRNA to investigate its effects on lung cancer cell proliferation, migration and apoptosis. Then we verified the interaction between β-catenin...
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Cellular Physiology and Biochemistry (2017) 43 (2): 757–767.
Published Online: 27 September 2017
...Xiaoxue Bai; Lin Meng; Huijie Sun; Zhuo Li; Xiufang Zhang; Shucheng Hua Background/Aims: Lung cancer is one of the most common causes of cancer related deaths worldwide. The role of several microRNAs (miRNAs) including miR-196b in different cancers has already been established. The study was aimed...
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