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1-20 of 85
Keywords: Invasion
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Journal Articles
Subject Area:
Further Areas
Lei Lang, Yixuan Hou, Yanlin Chen, Gang Tu, Jing Tao, Dan Yang, Lei Xi, Lixin Fu, Kexin Sun, Jiali Yin, Rui Chen, Meixi Peng, Shuiqing Liu, Manran Liu
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2019) 51 (6): 2972–2988.
Published Online: 14 December 2018
... was used to detect the cell migration and invasion abilities in different treatments. Quantitative phosphoproteome analysis was performed using hypoxic BT549 cells, in the presence or absence of Ku60019, a specific inhibitor of ATM kinase. The phosphorylated cortactin, the target protein of oxidized ATM...
Journal Articles
Subject Area:
Further Areas
Jing Wang, Guangnan Liu, Mengwei Liu, Li Xiang, Yizhi Xiao, Huiqiong Zhu, Xiaosheng Wu, Ying Peng, Wenjing Zhang, Ping Jiang, Aimin Li, Qingzhen Nan, Ye Chen, Chudi Chen, Tianming Cheng, Side Liu, Jide Wang
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2019) 51 (6): 2547–2563.
Published Online: 11 December 2018
... immunohistochemistry, flow cytometry, western blot, EdU incorporation, luciferase, chromatin Immunoprecipitation (ChIP) and cell invasion assays. Results: The CCDC43 gene was overexpressed in human CRC. High expression of CCDC43 protein was associated with tumor progression and poor prognosis in patients with CRC...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (3): 1276–1286.
Published Online: 27 November 2018
... with metformin in this study. Western blot assay was performed to detect th level of Bcl-2, Bax and Caspase-3. Scratch wound assay, transwell assay and Millicell invasion assay were used to assay the invasion and migration of EC9706 and Eca109 cells. Nude mice tumor models were used to assay the growth and lung...
Journal Articles
Subject Area:
Further Areas
Junfeng Zhang, Longsheng Wang, Shiyu Mao, Mengnan Liu, Wentao Zhang, Ziwei Zhang, Yadong Guo, Bisheng Huang, Yang Yan, Yong Huang, Xudong Yao
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (2): 513–527.
Published Online: 20 November 2018
... than the corresponding non-cancerous tissues. The methylation status of CpG islands was involved in the regulation of miR-1-3p expression. miR-1-3p inhibited the bladder cancer cell proliferation, migration, and invasion by directly targeting the 3’-UTR of glutaminase. It also exerted an anti-tumor...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 50 (3): 810–822.
Published Online: 23 October 2018
... the cell proliferation, migration/invasion, and apoptosis respectively. Results: Our study explored the expression profiles of KIF2A and miR-206 in the patients with ovarian cancer. We found that overexpression of KIF2A was associated with a poor prognosis in ovarian cancer. We also found that KIF2A mRNA...
Journal Articles
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Further Areas
Long Hai, Peidong Liu, Shengping Yu, Li Yi, Zhennan Tao, Chen Zhang, Iruni Roshanie Abeysekera, Tao Li, Luqing Tong, Haiwen Ma, Bo Liu, Yang Xie, Xingchen Zhou, Yu Lin, Meng Zhu, Kai Zhang, Bingcheng Ren, Haolang Ming, Yubao Huang, Xuejun Yang
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2019) 51 (6): 2925–2937.
Published Online: 11 October 2018
... signaling and has been shown to promote glioma-initiating cells (GICs) in glioblastoma. The role of Jagged1 in GICs invasion and underlying molecular mechanisms remain unclear. Methods: Survival data from R2 genomics analysis, the Cancer Genome Atlas (TCGA), the Chinese Glioma Genome Atlas (CGGA...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 50 (1): 92–107.
Published Online: 02 October 2018
... tissues and adjacent normal lung tissues. Patients’ prognosis was evaluated using overall survival. The prognostic role of MARCH9 was tested with univariate and multivariate analyses. To confirm the effect of MARCH9 in cell proliferation and invasion, overexpression of MARCH9 was induced in two LAC cell...
Journal Articles
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Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (6): 2382–2395.
Published Online: 27 September 2018
... in glioblastoma invasion remain to be clarified. The aim of this study was to investigate the molecular mechanisms of NTSR1 in glioblastoma invasion. Methods: Cell migration and invasion were evaluated using wound-healing and transwell assays. Cell proliferation was detected using CCK-8. The expression of NTSR1...
Journal Articles
Subject Area:
Further Areas
Hong-Ming Zhu, Xue-Song Jiang, Hui-Zi Li, Lu-Xi Qian, Ming-Yu Du, Zhi-Wei Lu, Jing Wu, Xiao-Kang Tian, Qian Fei, Xia He, Li Yin
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (4): 1564–1576.
Published Online: 17 September 2018
... aimed to evaluate the detailed mechanisms of invasion, migration and metastasis of NPC cells. Methods: Quantitative reverse-transcription PCR (qRT-PCR) and Western blot were used to confirm the expression levels of miR-184 and Notch2. NPC cell invasion and migration were subsequently examined using...
Journal Articles
Subject Area:
Further Areas
Jin-Hua He, Yu-Guang Li, Ze-Ping Han, Jia-Bin Zhou, Wei-Ming Chen, Yu-Bing Lv, Meng-Ling He, Ji-Dong Zuo, Lei Zheng
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (4): 1539–1550.
Published Online: 13 September 2018
... of proliferation was measured using a WST-8 cell proliferation assay. Clone formation ability was assessed with a clone formation inhibition test. Cell invasion and migration capacity was evaluated by performing a Transwell assay. Relative gene expression was assessed using quantitative real-time polymerase chain...
Journal Articles
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Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (3): 911–919.
Published Online: 05 September 2018
.... This study was aimed to investigate cytotoxic effect of external qi of Yan Xin Qigong (YXQ-EQ) toward human lung adenocarcinoma A549 cells as well as its effect on signaling pathways promoting migration, invasion and epithelial-to-mesenchymal transition (EMT) in A549 cells. Methods: Cytotoxic effect of YXQ...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (1): 217–225.
Published Online: 23 August 2018
...) in the development of esophageal cancer. Methods: The expression of RUNX2 in esophageal carcinoma tissues and cells was investigated by qRT-PCR. Effects of RUNX2 on cell viability, apoptosis, migration and invasion were assessed using MTT assay, flow cytometry assay/western blot analysis, and Transwell assays...
Journal Articles
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Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (6): 2429–2440.
Published Online: 17 August 2018
... of CRC. Results: Our results indicated that SRGN overexpression was significantly associated with poor prognosis in CRC specimens. SRGN overexpression promoted CRC cell migration and invasion in vitro ; however, SRGN depletion exhibited contrasting effects. Mechanistic investigations revealed that HIF-1α...
Journal Articles
Subject Area:
Further Areas
Zhuo Xu, Guangchao Liu, Meng Zhang, Zhilei Zhang, Yuming Jia, Li Peng, Yanhong Zhu, Jianbin Hu, Runying Huang, Xiaonan Sun
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (6): 2596–2606.
Published Online: 17 August 2018
... protein level in duct carcinoma tissues. The transfection efficiency was confirmed by western blot and/or RT-qPCR assay. The proliferation of bile duct carcinoma cells was determined by MTT and colony formation assay. The invasion ability of bile duct carcinoma cells was evaluated with Transwell invasion...
Journal Articles
Subject Area:
Further Areas
Ya-hui Bai, Yun-bo Zhan, Bin Yu, Wei-Wei Wang, Li Wang, Jin-qiao Zhou, Ruo-kun Chen, Feng-jiang Zhang, Xin-wei Zhao, Wen-chao Duan, Yan-min Wang, Jun Liu, Jian-ji Bao, Zhen-Yu Zhang, Xian-zhi Liu
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (4): 1755–1770.
Published Online: 03 August 2018
.../immunohistochemical staining (IHC) in our cohort. CCK-8 assay, transwell migration assay, wound healing assay, clonogenic assay and tumorigenicity assay were used to compare the proliferation, invasion and migration ability of glioma cells with different expressions of CDH18. iTRAQ-based quantitative proteomic...
Journal Articles
Subject Area:
Further Areas
Yongze Liu, Han Zhou, Xiaofeng Ma, Chuanyao Lin, Ling Lu, Dingding Liu, Dengbin Ma, Xia Gao, Xiao Yun Qian
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (4): 1556–1562.
Published Online: 02 August 2018
... was used to examine cell proliferative ability. Flow cytometry was used to examine cell cycle distribution, the scratch test was employed to examine cell migration, and Transwell migration assay (Boyden chamber) was used to study cell invasion. Results: The optimal concentrations of prodigiosin and 5-FU...
Journal Articles
Subject Area:
Further Areas
Yanqin Zhang, Qianghua Hu, Guixin Li, Lili Li, Shoulei Liang, Yun Zhang, Jiayong Liu, Zhengfu Fan, Lin Li, Bingzheng Zhou, Yongxin Ruan, Xueli Yang, She’an Chen, Tianyang Mu, Guowen Wang, Shunbin Xiong
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (3): 1099–1111.
Published Online: 24 July 2018
.../+ mouse metastatic osteosarcomas. Accordingly, we investigated the role of ONZIN in human osteosarcoma metastasis. Methods: ONZIN function and its downstream targets were examined in osteosarcoma cell lines. Assays related to tumorigenesis and metastasis, including cell migration, invasion, clonogenic...
Journal Articles
Subject Area:
Further Areas
Zaosong Zheng, Fengjin Zhao, Dingjun Zhu, Jinli Han, Haicheng Chen, Yuhong Cai, Zhiliang Chen, Wenlian Xie
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 48 (3): 891–904.
Published Online: 20 July 2018
... Atlas (TCGA) database. Kaplan-Meier analysis was used to examine the prognostic value of LUCAT1 and CXCL2 in ccRCC patients. Loss and gain of function were performed to explore the effect of LUCAT1 on proliferation and invasion in ccRCC cells. Western blotting was performed to evaluate the underlying...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 47 (6): 2250–2260.
Published Online: 05 July 2018
... unknown. Methods: The expression of LPXN in bladder cancer cells and tissues was determined by real-time PCR, western blotting, and immunohistochemistry, respectively. The biological role of LPXN in bladder cancer cell proliferation, invasion, and angiogenesis was explored both in vitro and in vivo...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 47 (5): 1871–1882.
Published Online: 29 June 2018
... to investigate the effects of VB on glioblastoma cell proliferation, apoptosis, migration, and invasion as well as the mechanism involving signal transducer and activator of transcription 3 (STAT3) and Src homology 2 domain-containing protein tyrosine phosphatase 1 (SHP-1). Methods: U87 cells were assigned...
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