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Keywords: Interferons
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Cellular Physiology and Biochemistry (2018) 51 (3): 1103–1118.
Published Online: 26 November 2018
.... Cytokine-induced senescence (CIS) likewise depends on activation of the p16 Ink4a /Rb pathway, and consecutive inactivation of the E2F family of transcription factors. In the present study, we therefore analyzed the role of Ago2 in CIS. Methods: Human cancer cell lines were treated with interferon-gamma...