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1-20 of 39
Keywords: Insulin
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Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (2): 924–937.
Published Online: 22 November 2018
... dependent on irisin-activated adenosine monophosphate-activated protein kinase (AMPK). Meanwhile, AMPK signaling mediated the protective effects of irisin on INS-1E cell insulin secretory ability and survival as well. Additionally, irisin inhibited phosphorylation of NF-κB p65 while decreasing...
Journal Articles
Subject Area:
Further Areas
Patrycja Rachubik, Maria Szrejder, Dorota Rogacka, Irena Audzeyenka, Michał Rychłowski, Stefan Angielski, Agnieszka Piwkowska
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (1): 393–410.
Published Online: 19 November 2018
... investigated whether the AMPK-TRPC6 pathway is involved in insulin-dependent cytoskeleton reorganization and glucose uptake in cultured rat podocytes. Methods: Western blot and immunofluorescence analysis confirmed AMPKα and TRPC6 expression, the phosphorylation of proteins associated with actin cytoskeleton...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 50 (1): 378–384.
Published Online: 04 October 2018
...Vladimír Štrbák Thyrotropin releasing hormone (TRH; pGlu-His-ProNH2) is expressed also in pancreatic β cells where it is colocalized in secretory granules with insulin. High perinatal changes of the TRH gene expression and TRH concentrations in rat pancreatic islets coincide with the perinatal...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (3): 1037–1047.
Published Online: 07 September 2018
... in response to H-1-2 treatment was quantified by western blotting. The blood glucose, secreted insulin and serous lipid profiles were measured with ELISA kits. Results: We consolidated that HIF1α and Sirt1 was dysregulated in T2DM patients and subjected to H-1-2 modulation. H-1-2 significantly inhibited...
Journal Articles
Subject Area:
Further Areas
Pu Wang, Yu Cheng Lu, Jie Wang, Lan Wang, Hanry Yu, Yuan Fei Li, Alice Kong, Juliana Chan, Shaochin Lee
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 47 (1): 356–367.
Published Online: 11 May 2018
... to investigate the molecular mechanisms underlying the centrosome amplification triggered by high glucose, insulin and palmitic acid. Western blot analysis was used to quantify the level of protein and protein phosphorylation. Immunofluorescent staining was performed to detect centrosomes. ROS was quantified...
Journal Articles
Subject Area:
Further Areas
Agnieszka Polak, Ewa Harasim-Symbor, Barbara Malinowska, Irena Kasacka, Alicja Lewandowska, Adrian Chabowski
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 46 (2): 727–739.
Published Online: 29 March 2018
... of the cardiovascular system in hypertension. Abnormalities in glucose metabolism and insulin action are commonly detected in hypertensive animals. Thus, potential antihypertensive drugs should be investigated with respect to modulation of glucose homeostasis. Therefore, the aim of the present study was to evaluate...
Journal Articles
Subject Area:
Further Areas
Chong Chen, Songhua Wang, Qingjuan Hu, Lvming Zeng, Hailong Peng, Chao Liu, Li-Ping Huang, Hao Song, Yuping Li, Li-Hua Yao, Wei Meng
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 45 (2): 446–457.
Published Online: 24 January 2018
...Chong Chen; Songhua Wang; Qingjuan Hu; Lvming Zeng; Hailong Peng; Chao Liu; Li-Ping Huang; Hao Song; Yuping Li; Li-Hua Yao; Wei Meng Background/Aims: Islet beta cells (β-cells) are unique cells that play a critical role in glucose homeostasis by secreting insulin in response to increased glucose...
Journal Articles
Subject Area:
Further Areas
Hanieh Gholami, Sajad Jeddi, Azita Zadeh-Vakili, Khadije Farrokhfall, Fatemeh Rouhollah, Maryam Zarkesh, Mahboubeh Ghanbari, Asghar Ghasemi
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 43 (6): 2338–2352.
Published Online: 27 October 2017
... 2 diabetes. This study aims to address effects of TCH on mRNA expressions of glucose transporters (GLUTs) and glucokinase (GcK) in islets and insulin target tissues of aged offspring rats. Methods: The TCH group received water containing 0.025% 6-propyl-2-thiouracil during gestation. Offspring from...
Journal Articles
Subject Area:
Further Areas
Martin Jakab, Nina Ketterl, Johannes Fürst, Marlena Beyreis, Michael Kittl, Tobias Kiesslich, Cornelia Hauser-Kronberger, Martin Gaisberger, Markus Ritter
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 43 (3): 1037–1051.
Published Online: 02 October 2017
...Martin Jakab; Nina Ketterl; Johannes Fürst; Marlena Beyreis; Michael Kittl; Tobias Kiesslich; Cornelia Hauser-Kronberger; Martin Gaisberger; Markus Ritter Background/Aims: Glucose-stimulated insulin secretion (GSIS) of pancreatic β-cells involves glucose uptake and metabolism, closure of K ATP...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 43 (2): 870–878.
Published Online: 28 September 2017
... days, we observed the animal models for an additional 4 weeks. After body weights were measured, urinary albumin, urinary protein, SOD activity and malondialdehyde (MDA) were measured by ELISA, BCA and biochemical assay respectively . Moreover, plasma insulin was assayed by radioimmunoassay, insulin...
Journal Articles
Subject Area:
Topic Article Package: Pharmacology 2016
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Topic Article Package: Diabetes 2016
,
Topic Article Package: Diabetes
,
Further Areas
Michael Kittl, Marlena Beyreis, Munkhtuya Tumurkhuu, Johannes Fürst, Katharina Helm, Anna Pitschmann, Martin Gaisberger, Sabine Glasl, Markus Ritter, Martin Jakab
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 39 (1): 278–293.
Published Online: 24 June 2016
... treatment in Traditional Mongolian Medicine. The flavonoid quercetin and its glycoside rutin, which exert anti-diabetic properties in vivo by interfering with insulin signaling in peripheral target tissues, are constituents of these extracts. This study was performed to better understand short- and long...
Journal Articles
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 38 (2): 659–669.
Published Online: 08 February 2016
...Shengqiang Xia; Ying Liu; Xinming Li; Florian Thilo; Martin Tepel Background/Aims: Insulin signaling to podocytes is relevant for the function of the glomerulus. Now, we tested the hypothesis that insulin increases the surface expression of canonical transient receptor potential canonical type 6...
Journal Articles
Chunchun Han, Shouhai Wei, Qi Song, Fang He, Xiangping Xiong, Huofu Wan, Dandan Liu, Fengjiang Ye, Hehe Liu, Liang Li, Hongyong Xu, Xiaohui Du, Bo Kang, Xianyin Zeng
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 38 (2): 558–570.
Published Online: 05 February 2016
... hypothesize that insulin acts goose hepatocellular growth by PI3K-Akt-mTOR signal pathway. Because the physiological status of liver cells in vitro is different from that in vivo , a simplified cell model in vitro was established. Methods: Goose primary hepatocytes were isolated and incubated in either...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 37 (4): 1407–1420.
Published Online: 22 October 2015
... water for 24 weeks. All rats were fed with the standard diet with or without resveratrol. Results: High-fructose diet increased plasma insulin, triglyceride and VLDL levels as well as omental weights in both genders. Long-term dietary fructose causes marked increase in body weight of males...
Journal Articles
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 37 (3): 1029–1043.
Published Online: 25 September 2015
..., instructions or products referred to in the content or advertisements. Nutrition Food Diet Depression Microbiota Leptin Ghrelin IGF BDNF Insulin By the year 2020, depression is projected to reach second place in the ranking of disability adjusted life years calculated for all ages...
Journal Articles
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 37 (1): 284–296.
Published Online: 24 August 2015
... trafficking could activate the unfolded protein response (UPR) by up-regulating the expression levels of activating transcription factor-6 (ATF-6) and the ER chaperone protein calnexin. In addition, we demonstrated that 100 nM insulin up-regulated the expression of the hERG channel and rescued the hERG...
Journal Articles
Layla Amiri, Annie John, Jasmin Shafarin, Ernest Adeghate, Petrilla Jayaprakash, Javed Yasin, Frank Christopher Howarth, Haider Raza
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 36 (5): 1939–1950.
Published Online: 17 July 2015
...Layla Amiri; Annie John; Jasmin Shafarin; Ernest Adeghate; Petrilla Jayaprakash; Javed Yasin; Frank Christopher Howarth; Haider Raza Background/Aim: Type 2 diabetes is the most common metabolic disorder, characterized by insulin resistance and pancreatic islet beta-cell failure. The most common...
Journal Articles
Eduardo L. Nolasco, Fernando L. Zanoni, Fernanda P. B. Nunes, Sabrina S. Ferreira, Luiza A. Freitas, Mariana C.F. Silva, Joilson O. Martins
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 36 (4): 1467–1479.
Published Online: 06 July 2015
... to investigate the effect of insulin on the local environment after cecal ligation and puncture (CLP) in rats. Methods: Diabetic (alloxan, 42 mg/kg i.v., 10 days) and non-diabetic (control) male Wistar rats were subjected to a two-puncture CLP procedure and 6 h later, the following analyses were performed...
Journal Articles
Karen K. S. Sunahara, Fernanda P. B. Nunes, Marisa A. P. Baptista, Carina Strell, Paulina Sannomiya, Lisa S. Westerberg, Joilson O. Martins
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2014) 34 (6): 2017–2026.
Published Online: 26 November 2014
...Karen K. S. Sunahara; Fernanda P. B. Nunes; Marisa A. P. Baptista; Carina Strell; Paulina Sannomiya; Lisa S. Westerberg; Joilson O. Martins Background/Aims: Diabetes mellitus (DM) is characterized by hyperglycemia, associated to a lack or inefficiency of the insulin to regulate glucose metabolism...
Journal Articles
Subject Area:
Further Areas
Luca Giudici, Ana Velic, Arezoo Daryadel, Carla Bettoni, Nilufar Mohebbi, Thomas Suply, Klaus Seuwen, Marie-Gabrielle Ludwig, Carsten A. Wagner
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2013) 32 (5): 1403–1416.
Published Online: 28 November 2013
... by extracellular protons in the physiological pH range (i.e. pH 7.7 - 6.8) and is coupled to the production of cAMP. Methods: We examined mice lacking GPR4 and examined glucose tolerance and insulin sensitivity in young and aged mice as well as in mice fed with a high fat diet. Expression profiles of pro- and anti...
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