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Journal Articles

Mesangial Medium from IgA Nephropathy Patients Induces Podocyte Epithelial-to-mesenchymal Transition through Activation of the Phosphatidyl Inositol-3-kinase/Akt Signaling Pathway

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Cheng Wang, Xun Liu, ZunFu Ke, Ying Tang, Cui-Cui Li, Can-Ming Li, ZengChun Ye, Jun Zhang, Tanqi Lou
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2012) 29 (5-6): 743–752.
https://doi.org/10.1159/000170949
Published Online: 11 May 2012
... for podocyte damage. This study hypothesized that conditioned mesangial medium may induced EMT process of podocytes and thereby lead to glomerular injury or sclerosis. Materials and Methods: Podocytes were incubated in medium from mesangial cells incubated with aggregated IgA1(aIgA1) isolated from IgAN...
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