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Keywords: Histone deacetylase
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Journal Articles
Subject Area:
Further Areas
Patrick Lugenbiel, Katharina Govorov, Ann-Kathrin Rahm, Teresa Wieder, Dominik Gramlich, Pascal Syren, Nadine Weiberg, Claudia Seyler, Hugo A. Katus, Dierk Thomas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 49 (1): 65–77.
Published Online: 22 August 2018
.... Underlying epigenetic regulation of cardiac electrophysiology remains incompletely understood. Histone deacetylases (HDACs) control gene expression and cardiac integrity. We hypothesized that class I/II HDACs transcriptionally regulate ion channel expression and determine action potential duration (APD...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 46 (5): 1821–1834.
Published Online: 25 April 2018
...Daishun Liu; Honglan Zhu; Ling Gong; Shenglan Pu; Yang Wu; Wei Zhang; Guichuan Huang Background/Aims: Epithelial to mesenchymal transition (EMT) is a crucial process involved in pulmonary fibrosis. This study aimed to explore the role of histone deacetylases (HDACs) and endoplasmic reticulum (ER...
Journal Articles
Subject Area:
Further Areas
Ning Hu, Changdong Wang, Xi Liang, Liangjun Yin, Xiaoji Luo, Bo Liu, Hongyu Zhang, Wei Shui, Guoxin Nan, Ning Wang, Ningning Wu, Xian Chen, Yunfeng He, Sheng Wen, Fang Deng, Hongmei Zhang, Zhan Liao, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, Wei Huang
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2013) 32 (2): 486–498.
Published Online: 30 August 2013
... in regulating the stem cell potency and lineage commitment. Here, we investigate if the inhibition of histone deacetylases (Hdacs) affects BMP9-induced osteogenic differentiation of MSCs. Methods: Using the Hdac inhibitor trichostatin A (TSA), we assess that TSA enhances BMP9-mediated osteogenic markers...