...YuSheng Cheng; XiaoLong Chen; LinSen Ye; YinCai Zhang; Jing Liang; Wei Liu; BoXuan Zhou; ShiYang Zheng; Yiming Huang; GuiHua Chen; YiNan Deng; Qi Zhang; Yang Yang Background/Aims: Numerous studies have shown that NIMA-related kinase 2 ( NEK2 ) expression in hepatocellular carcinoma (HCC) tissue...

... a key role in the progression of hepatocellular carcinoma (HCC). However, the molecular mechanisms by which SNHG8 contributes to HCC remain elusive and merit exploration. Methods: The association between SNHG8 expression and the clinicopathological characteristics and prognoses in HCC patients...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. microRNA-183 Tumor Suppressor Hepatocellular Carcinoma HepG2 cell line...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. EMT Hepatocellular carcinoma LATS2 miR-650 YAP Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide [ 1 ]. The prognosis...

...Chenxing Zhang; Chenyue Zhang; Jiamao Lin; Haiyong Wang Background/Aims: An increasing number of studies have suggested that circular RNAs (circRNAs) have vital roles in carcinogenesis and tumor progression. However, the function of circRNAs in hepatocellular carcinoma (HCC) remains poorly...

... is associated with EMT, but whether miR-197 regulatesWnt/β-catenin remains unclear. This study was to demonstrate the role of miR-197 on the Wnt/β-catenin pathway in hepatocellular carcinoma (HCC). Methods: Quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to detect the expression...

...Dong Wang; Zhi-Ming Wang; Sai Zhang; Hai-Jun Wu; Yi-Ming Tao Background/Aims: Canopy homolog 2 (CNPY2) is a signature gene highly associated with tumor progression, including hepatocellular carcinoma (HCC). The presence of tumor hemorrhage (TH) implies a fast-growing and worse tumor...

...Le Bao; Lei Yuan; Pengfei Li; Qingyun Bu; Aijun Guo; Hui Zhang; Ning Cui; Bin Liu Background/Aims: The roles and related mechanisms of RNA binding protein FUS (fused in sarcoma/translocated in liposarcoma) are unclear in numerous cancers, including hepatocellular carcinoma (HCC). Methods...

...Yujia Pan; Simeng Tong; Rongjun Cui; Jialin Fan; Chi Liu; Yucui Lin; Jiebing Tang; Hui Xie; Ping Lin; Tianhu Zheng; Xiaoguang Yu Background/Aims: Hepatocellular carcinoma (HCC) has a high morbidity as well as mortality and is believed to be one of the most prevalent cancers worldwide. The long non...

...Lixiong He; Yujing Huang; Qiaonan Guo; Hui Zeng; Chuanfen Zheng; Jia Wang; Ji-an Chen; Lingqiao Wang; Weiqun Shu Background/Aims: Our recent study indicated that the serum microcystin-LR (MC-LR) level is positively linked to the risk of human hepatocellular carcinoma (HCC). Gankyrin is over...

...Ying Liu; Cheng Hu; Wen-Bo Zhu; Wen-Xiong Xu; Zhan-Yi Li; Yuan Lin; Jing Cai; Jian-kai Liang; Xiang Zhu; Zhi-Liang Gao; Guang-mei Yan; Liang Peng Background/Aims: Zinc finger antiviral protein (ZAP) has been reported to be expressed in hepatocellular carcinoma (HCC), and ZAP expression...

...Peng Lin; Dong-yue Wen; Qing Li; Yun He; Hong Yang; Gang Chen Background/Aims: Hepatocellular carcinoma (HCC) is the most prevalent subtype of primary liver tumor worldwide. Growing evidence has led to a consensus that long non-coding RNAs (lncRNAs) have considerable influence on tumorigenesis...

... RNA (lncRNA) biomarkers for predicting survival in patients with hepatocellular carcinoma (HCC) using The Cancer Genome Atlas (TCGA) dataset and bioinformatics analysis. Methods: RNA sequencing and clinical data of HCC patients from TCGA were used for prognostic association assessment by univariate...

... investigated the clinical significance and biological function of miR-142-3p in hepatocellular carcinoma (HCC). Methods: The expression levels of taurine upregulated gene 1 (TUG1), miR-142-3p, and zinc finger E-box-binding homeobox 1 (ZEB1) were evaluated in HCC tissues and cell lines by quantitative real-time...

...Ying Mei; Yu You; Jin Xia; Jian-Ping Gong; Yun-Bing Wang Background/Aims: Few studies have been designed to directly investigate the exact mechanisms underlying the different phenotypes between cirrhotic and non-cirrhotic hepatocellular carcinoma (HCC). This study aimed to illuminate the incidence...

... of NEAT1 in hepatocellular carcinoma (HCC). Methods: The effects of NEAT1 on cell proliferation, apoptosis, migration, and invasion were measured by in vitro experiments. The expression level and clinical value of NEAT1 in HCC was evaluated based on data from The Cancer Genome Atlas (TCGA), Oncomine...

... carcinoma. The aim of the current study was to identify biochemical measures that could affect patient prognosis after liver transplantation. Methods: A total of 119 patients receiving liver transplantation for hepatocellular carcinoma were used to construct a model for predicting recurrence. The results...

... in carcinogenesis. However, the expression and prognostic value of CPT1A in hepatocellular carcinoma (HCC) have not been extensively studied. Methods: Here, we collected 66 post-operative liver cancer tissue samples. Gene profile expression was tested by RT-PCR. Receiver operating characteristic (ROC) analysis...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. RNA-editing Sequencing Hepatocellular carcinoma ADAR1 Prognosis Hepatocellular carcinoma (HCC) is one of the most common cancer...

... to in the content or advertisements. SKP2 CARM1 Autophagy AMPK Hepatocellular Carcinoma Hepatocellular carcinoma (HCC) is the sixth most frequent tumor with an accelerating incidence in recent years. Over 750, 000 new cases are reported per year worldwide [ 1-3 ]. Approximately 10% to 15% have...