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Keywords: Genistein
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Cellular Physiology and Biochemistry (2018) 47 (4): 1667–1681.
Published Online: 27 June 2018
...Ying Lan; Xiulian Li; Xuebo Liu; Cui Hao; Ni Song; Sumei Ren; Wei Wang; Ningchuan Feng; Lijuan Zhang Background/Aims: Genistein is a natural isoflavone enriched in soybeans. It has beneficial effects for patients with mucopolysaccharidose type III through inhibiting glycosaminoglycan biosynthesis...
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Cellular Physiology and Biochemistry (2016) 40 (1-2): 335–346.
Published Online: 21 November 2016
...Shawn Catmull; Faisal Masood; Sydney Schacht; Robert Dolan; Daniel Stegman; Lana Leung; Layla Al-Nakkash Background/Aims: The goal of this study was to determine the effect of dietary genistein (naturally occurring phytoestrogen) on jejunal secretory function in a clinically relevant model...
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Cellular Physiology and Biochemistry (2015) 35 (5): 2069–2077.
Published Online: 01 April 2015
...Jian Qin; Jia Xin Chen; Zhou Zhu; Jia An Teng Background: Genistein, a major isoflavonoid isolated from dietary soybean, has been shown to suppress the growth of several cancers through modulation of various pathways. However, the molecular mechanisms by which genistein elicit its effects...
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Cellular Physiology and Biochemistry (2015) 35 (4): 1317–1325.
Published Online: 12 February 2015
...Lana Leung; Ashesh Bhakta; Katherine Cotangco; Layla Al-Nakkash Background/Aims: We have previously shown that daily subcutaneous injections with the naturally occurring phytoestrogen genistein (600 mg genistein/kg body weight/day, 600G) results in a significantly increased basal intestinal...
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Cellular Physiology and Biochemistry (2013) 31 (1): 80–91.
Published Online: 22 January 2013
... effects, including long QT syndrome (LQTs) and even sudden cardiac death. Previous studies have shown that genistein (Gen) exerts anti-oxidant, anti-inflammatory, and anti-apoptotic effects. The present study aimed to explore the potential protective effects of Gen on As 2 O 3 -induced adverse cardiac...
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Cellular Physiology and Biochemistry (2012) 30 (1): 137–150.
Published Online: 18 June 2012
...Layla Al-Nakkash Background/Aims: Daily subcutaneous injections with the phytoestrogen genistein, 600 mg/ kg genistein/day (600G) significantly increased intestinal chloride (Cl - ) secretion (I sc , µA/cm 2 ) in C57BL/6J female and male murine jejunum after 1-2-weeks treatment. Methods and Results...
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Cellular Physiology and Biochemistry (2011) 28 (2): 239–250.
Published Online: 16 August 2011
...Layla Al-Nakkash; Lyn Batia; Minoti Bhakta; Amity Peterson; Nathan Hale; Ryan Skinner; Steven Sears; Jesse Jensen Background/Aims: The effect of daily injections with genistein (naturally occurring phytoestrogen) on intestinal chloride (Cl - ) secretion was measured with Ussing chamber short...
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Cellular Physiology and Biochemistry (2010) 26 (3): 431–440.
Published Online: 24 August 2010
...Mi Jeong Sung; Duk-Hoon Kim; Munkhtugs Davaatseren; Haeng Jeon Hur; Won Kim; Yu Jin Jung; Sung Kwang Park; Dae Young Kwon Genistein is a polyphenolic nonsteroidal isoflavonoid with estrogen-like activity has been shown to have anticancer, antioxidant, and anti-inflammatory activities. Fractalkine...
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Cellular Physiology and Biochemistry (2009) 24 (3-4): 161–166.
Published Online: 03 August 2009
... (CPA, a SR-Ca 2+ ATPase inhibitor), but SR-Ca 2+ load was reduced. Genistein (a tyrosine kinase inhibitor) slowed down the Ca 2+ undershoot drop and the SR-Ca 2+ load but did not affect the undershoot recovery rate. Ni 2+ (a capacitative Ca 2+ inhibitor), but neither SKF-96365 (a passive Ca 2+ entry...
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Cellular Physiology and Biochemistry (2007) 20 (5): 473–482.
Published Online: 29 April 2008
... of endocytosis in F508delCFTR fibroblasts, which was absent in genistein- or cyclodextrin-treated cultures.Conclusion: The results not only suggest that reducing cellular cholesterol may serve as pharmacotherapeutic tool in the treatment of cystic fibrosis but also reveal a novel mechanism for genistein...