... the effect of epigenetics on metabolic memory, we analyzed the impact of transient high-glucose stimulation on the secretion of inflammatory factors from rat glomerular mesangial cells. Methods: Rat glomerular mesangial cells (HBZY-1) were divided into three groups: high-glucose group (25 mM glucose...

...Yue Teng; Xiaohang Zuo; Meng Hou; Yan Zhang; Chen Li; Wenjuan Luo; Xu Li Background: Epigenetic abnormalities are increasingly observed in multiple malignancies, including epithelial ovarian cancer (EOC), and their effects can be significantly counteracted by tumor-suppressor microRNAs, namely epi...

... managed to elucidate underlying mechanisms, with epigenetics having become almost synonymous with developmental programming. The aim of this review was to give a comprehensive overview of various aspects and mechanisms of developmental origins of diseases. Starting from initial research foci mainly...

..., instructions or products referred to in the content or advertisements. AlkB AlkB homologs ALKBH1 NANOG SOX2 Epigenetics Histone demethylation Embryonic stem cells Pluripotency Histone H2A In E. coli , the AlkB protein is involved in repair of methylations-induced DNA damage by oxidative...

...Claudia Philippeit; Maike Busch; Nicole Dünker Background: Recent studies demonstrated that epigenetic mechanisms are involved in the regulation of trefoil factor family (TFF) peptide expression in cancer. In human tissues with endogenous TFF1, TFF2 or TFF3 gene expression, the corresponding...

... and DHA on the epigenetic regulation of human neuronal cells and highlight the potential benefit of dietary intake of DHA for management of neurodegenerative diseases. Zinc Omega-3 fatty acid DHA M17 human neuronal cell Histone H3 post-translational modification Epigenetics Cellular Physiology...

..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. SLC26A4 Epigenetics CpG Bisulfite modification NCI-H292 HEK-Blue Cellular...