...Jin-Sun Lee; Hong Jae Lee; Jae Won Lee; Sang Cheon Lee; Jung Sun Heo Background/Aims: This study investigated the effect of inducible nitric oxide synthase-loaded mineralized nanoparticles (iNOS-MNPs) on the osteogenic differentiation of mouse embryonic stem cells (ESCs). Methods: We prepared iNOS...

...Hong-Xi Zhao; Feng Jiang; Ya-Jing Zhu; Li Wang; Ke Li; Yang Li; Xiao-Hong Wang; Ling-Song Li; Yuan-Qing Yao Background: Despite the great potential of utilizing human embryonic stem cells (hESCs)-derived cells as cell source for transplantation, these cells were often rejected during engraftment...

... are very limited. To study the effects of altered gravity on the embryonic development processes we established an in vitro methodology allowing differentiation of mouse embryonic stem cells (mESCs) under simulated microgravity within a fast-rotating clinostat (clinorotation) and capture of microarray...

... mice lacking Alkbh1 reveal that most Alkbh1 -/- embryos die during embryonic development. Embryonic stem cells (ESCs) derived from these mice have prolonged expression of pluripotency markers and delayed induction of genes involved in neural differentiation, indicating that ALKBH1 is involved...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Embryonic stem cells Bioactive peptides NCAM Differentiation Cardiomyocyte Cardiac diseases, causing severe...

...Tobias Hannes; Marie Wolff; Michael Xavier Doss; Kurt Pfannkuche; Moritz Haustein; Jochen Müller-Ehmsen; Agapios Sachinidis; Jürgen Hescheler; Markus Khalil; Marcel Halbach Background: Modelling of cardiac development, physiology and pharmacology by differentiation of embryonic stem cells (ESCs...

...David R. Christensen; Philip C. Calder; Franchesca D. Houghton Background/Aims: Human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Ventricle Embryonic stem cells Differentiation Puerarin Cardiomyocytes Currently, cardiomyocytes (CMs) derived from embryonic stem (ES...

..., instructions or products referred to in the content or advertisements. Embryonic stem cells Cardiomyocytes Baicalin Differentiation Baicalin is a well-known cardiovascular protective agent that is isolated from a plant Scutellaria baicalensis [ 8,9,10 ]. It has been shown that baicalin promotes...

..., we cocultured murine embryonic stem cells (mES) with murine embryonic ventricular myocytes (mEVs) in hanging drops to assess the cellular interaction and function of mES-derived cardiomyocytes under these conditions. Results: We found that when mEVs are added to a culture system of embryonic stem...

... Words iPS Induced pluripotent stem cells Embryonic stem cells Reprogramming Pluripotency Cardiovascular diseases cells are identical, and we finish with an outlook on clinical research with iPS cells with a focus on cardiovascular medicine. Copyright © 2010 S. Karger AG, Basel Abstract...