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Keywords: ERAD
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Journal Articles
B-Cell Receptor-Associated Protein 31 Regulates the Expression of Valosin-Containing Protein Through Elf2
Open AccessSubject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (4): 1799–1814.
Published Online: 30 November 2018
... following both shRNA- and siRNA-mediated knockdown of Bap31. Both the mRNA and protein levels of VCP were regulated by Bap31 in vivo and in vitro . In the ER-associated degradation (ERAD) pathway, Bap31 also regulated VCP expression and caused differences in the binding quantities of CFTRΔF508 and VCP...
Journal Articles
BAG-1 Stabilizes Mutant F508del-CFTR in a Ubiquitin-Like-Domain-Dependent Manner
Available to PurchaseSubject Area:
Further Areas
Filipa Mendes, Carlos M. Farinha, Verónica Felício, Paulo C. Alves, Isabel Vieira, Margarida D. Amaral
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2012) 30 (5): 1120–1133.
Published Online: 05 October 2012
... F508del-CFTR by direct binding, probably competing out ubiquitin to partially avoid its proteasomal degradation. Cystic Fibrosis CFTR ERAD BAG-1 Hsp70 Ubiquitin 13 09 2012 5 10 2012 © 2012 S. Karger AG, Basel 2012 Copyright / Drug Dosage / Disclaimer Copyright: All rights...
