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Keywords: ER-Stress
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Journal Articles

Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells

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Barbora Chovancova, Sona Hudecova, Lubomira Lencesova, Petr Babula, Ingeborg Rezuchova, Adela Penesova, Marian Grman, Roman Moravcik, Michal Zeman, Olga Krizanova
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 44 (2): 763–777.
https://doi.org/10.1159/000485290
Published Online: 23 November 2017
... cells. Methods: We compared the effect of 24 h melatonin treatment on calcium transport (by fluorescent probes FLUO-3AM and Rhod-5N), ER stress (determined as changes in the expression of CHOP, XBP1 and fluorescently, using Thioflavin T), ROS formation (by CellROX® Green/Orange Reagent) and apoptosis...
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Journal Articles

Anti-Leukemic Activity of Shikonin: Role of ERP57 in Shikonin Induced Apoptosis in Acute Myeloid Leukemia

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Rachana Trivedi, Gerhard A. Müller, Manohar S. Rathore, Durga P. Mishra, Hassan Dihazi
Journal: Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2016) 39 (2): 604–616.
https://doi.org/10.1159/000445652
Published Online: 15 July 2016
...Rachana Trivedi; Gerhard A. Müller; Manohar S. Rathore; Durga P. Mishra; Hassan Dihazi Background/Aims: ER-Stress and activation of unfolded protein response belong to the major factors involved in chemoresistance in cancer cells. In this study we investigated the effect of shikonin on the survival...
View articletitled, Anti-Leukemic Activity of Shikonin: Role of ERP57 in Shikonin Induced Apoptosis in Acute Myeloid Leukemia
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