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Keywords: EMT
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Journal Articles
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Cellular Physiology and Biochemistry (2019) 51 (6): 2829–2842.
Published Online: 18 December 2018
... and metastasis in vitro and in vivo . Markers of epithelial to mesenchymal transition (EMT) were evaluated by western blotting. Immunohistochemistry (IHC) was used to analyse the relationship between CUL4A expression and E-cadherin expression. Results: CUL4A and TP53 protein expression was significantly higher...
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Cellular Physiology and Biochemistry (2019) 51 (6): 2794–2813.
Published Online: 12 December 2018
...Manshu Yu; Jun Shi; Meixiao Sheng; Kun Gao; Lu Zhang; Li Liu; Yilin Zhu Background/Aims: The epithelial-to-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) is a crucial event in the induction of peritoneal fibrosis (PF), in which canonical Wnt/β-catenin signaling participates...
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Cellular Physiology and Biochemistry (2018) 51 (5): 2085–2097.
Published Online: 06 December 2018
..., instructions or products referred to in the content or advertisements. Diabetic nephropathy Gliquidone Renal tubular epithelium EMT Renal interstitial fibrosis Notch/Snail1 signaling pathway Diabetes has become the third most common chronic non-communicable disease threatening human health...
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Cellular Physiology and Biochemistry (2018) 51 (3): 1179–1192.
Published Online: 27 November 2018
...Li Li Han; Xiao Ran Yin; Shu Qun Zhang Background/Aims: Previous studies have confirmed that microRNAs are involved in the metastasis and epithelial–mesenchymal transition (EMT) of malignancies. In this study, we examined whether miR-650 promotes the migration, invasion, and EMT of hepatocellular...
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Cellular Physiology and Biochemistry (2018) 51 (1): 470–486.
Published Online: 19 November 2018
...Zhaoxia Hu; Peipei Wang; Jiaxin Lin; Xingrong Zheng; Fangji Yang; Genglin Zhang; Dabiao Chen; Junqiang Xie; Zhiliang Gao; Liang Peng; Chan Xie Background/Aims: MicroRNA-197 (miR-197) has been shown to play roles in epithelialmesenchymal transition (EMT) and metastasis. The Wnt/β-catenin pathway...
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Journal Articles
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Cellular Physiology and Biochemistry (2018) 50 (6): 2124–2138.
Published Online: 09 November 2018
... and promoting apoptosis, whereas HOXA-AS2 overexpression promoted cell growth. Further functional assays indicated that HOXA-AS2 significantly promoted HCC cell migration and invasion by promoting EMT. Bioinformatics online programs predicted that HOXA-AS2 sponge miR-520c-3p at 3’-UTR with complementary binding...
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Cellular Physiology and Biochemistry (2018) 50 (2): 501–511.
Published Online: 11 October 2018
..., the mechanisms underlying CDC27-induced the epithelial-mesenchymal transition (EMT) of GC are still unclear. Methods: We analyzed the expression levels of CDC27 and EMT-related biomarkers using immunohistochemistry and Western blot in 60 cases of GC tissues, and then GC cells with CDC27 shRNAs or plasmids were...
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Cellular Physiology and Biochemistry (2018) 49 (4): 1564–1576.
Published Online: 17 September 2018
... of invading NPC cells, whereas miR-184 mimics inhibited the invasive ability of such cells. The protein level of E-cadherin decreased, whereas those of N-cadherin and vimentin increased in the anti-miR-184 group. This result showed that miR-184 inhibited NPC cell invasion and metastasis by regulating EMT...
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Cellular Physiology and Biochemistry (2018) 49 (3): 1060–1073.
Published Online: 07 September 2018
... was determined by chromatin immunoprecipitation (ChIP) assays. Results: FGF18 promoted the epithelial-mesenchymal transition (EMT) and migration in breast cancer cells through activation of the Akt/GSK3β/β-catenin pathway. FGF18 increased Akt-Ser473 and -Thr308 phosphorylation, as well as that of GSK3β-Ser9...
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Cellular Physiology and Biochemistry (2018) 49 (3): 911–919.
Published Online: 05 September 2018
.... This study was aimed to investigate cytotoxic effect of external qi of Yan Xin Qigong (YXQ-EQ) toward human lung adenocarcinoma A549 cells as well as its effect on signaling pathways promoting migration, invasion and epithelial-to-mesenchymal transition (EMT) in A549 cells. Methods: Cytotoxic effect of YXQ...
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Cellular Physiology and Biochemistry (2018) 49 (2): 501–511.
Published Online: 29 August 2018
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Prodigiosin Pulmonary Fibrosis miR-410 TGF-β1 ADAMTS-1 EMT...
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Cellular Physiology and Biochemistry (2018) 49 (1): 260–270.
Published Online: 23 August 2018
... measured by MTT, flow cytometry, and transwell assays, respectively. Expression levels of different mRNAs and proteins associated with apoptosis, epithelial mesenchymal transition (EMT), β-catenin, MAPK, and PI3K/AKT pathways were assessed by RT-qPCR and western blot analysis, respectively. The tumor...
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Cellular Physiology and Biochemistry (2018) 48 (6): 2429–2440.
Published Online: 17 August 2018
..., methods, instructions or products referred to in the content or advertisements. Srgn HIF1α Colorectal cancer Metastasis Invasion EMT In the United States, there are estimated more than 1.4 million men and women living with a diagnosis of colorectal cancer (CRC) [ 1 ]. With high...
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Cellular Physiology and Biochemistry (2018) 48 (4): 1703–1709.
Published Online: 03 August 2018
... cells with ITCH deficiency. Conclusions: Inhibition of ITCH might suppress lung cancer proliferation and invasion via regulation of MMPs, EMT and Bcl2/Bax signaling pathway. zhangqigang_xw@163.com 28 12 2017 23 07 2018 3 8 2018 © 2018 The Author(s). Published by S. Karger AG...
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Cellular Physiology and Biochemistry (2018) 48 (1): 158–172.
Published Online: 12 July 2018
... had significant prognostic value in carbohydrate antigen 19-9 (CA19-9) negative patients. The expression of FXR was negatively correlated with IL-6 levels in clinical ICC tissues. FXR inhibited the proliferation, migration, invasion and epithelial mesenchymal transition (EMT) of ICC cells via...
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Cellular Physiology and Biochemistry (2018) 48 (1): 138–148.
Published Online: 12 July 2018
...Zhuo Gao; Ruiqi Liu; Na Ye; Chao Liu; Xiuli Li; Xiaodong Guo; Zhuoran Zhang; Xiaoxi Li; Yuanfei Yao; Xiaofeng Jiang Background/Aims: Cell surface morphology plays pivotal roles in malignant progression and epithelial-mesenchymal transition (EMT). Previous research demonstrated that microvilli play...
Journal Articles