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Keywords: Diabetic nephropathy
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Cellular Physiology and Biochemistry (2018) 51 (5): 2085–2097.
Published Online: 06 December 2018
...Hengyu Tian; Junbo Yang; Zhuochao Xie; Jialin Liu Background/Aims: Diabetic nephropathy is a common complication of diabetes. This study explored the renal protective effect and possible mechanism of gliquidone in mice with diabetic nephropathy. Methods: Animal model of diabetic nephropathy...
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Cellular Physiology and Biochemistry (2018) 49 (5): 1747–1754.
Published Online: 19 September 2018
...Deng Yunlei; Fan Qiuling; Wang Xu; Zhao Qianwen; Cao Xu; Xu Li; Wang Lining Background/Aims: Diabetic nephropathy is the one of the most serious microvascular complications of diabetes mellitus, and “metabolic memory” plays a vital role in the development of diabetic complications. To investigate...
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Cellular Physiology and Biochemistry (2018) 46 (2): 713–726.
Published Online: 29 March 2018
..., such as methylglyoxal (MG), contribute to diabetic complications. MG-scavenging capacities of carnosine and anserine, which have been shown to mitigate diabetic nephropathy, were evaluated in vitro and in vivo . Methods: MG-induced cell toxicity was characterized by MTT and MG-H1-formation, scavenging abilities...
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Cellular Physiology and Biochemistry (2018) 45 (5): 1747–1758.
Published Online: 23 February 2018
... patients with moderate renal impairment. As its effect on kidney function is discrepant and complicated, the aim of this study is to determine the effect of dapagliflozin on the progression of diabetic nephropathy and related mechanisms. Methods: Twelve-week-old male C 57 BL/6 wild-type and db/db mice were...
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Cellular Physiology and Biochemistry (2017) 43 (2): 685–696.
Published Online: 22 September 2017
...Suxia Yang; Junwei Zhang; Shiying Wang; Jun Shi; Xinxin Zhao Background/Aims: Angiopoietin-like protein 2 (ANGPTL2) was reported to be implicated in the pathogenesis of inflammatory disease. Its role in diabetic nephropathy (DN) remained illdefined. Methods: qRT-PCR and western blot analysis were...
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Cellular Physiology and Biochemistry (2017) 43 (1): 39–51.
Published Online: 24 August 2017
...Jia Guo; Congqun Lu; Fangxing Zhang; Haixia Yu; Mengwen Zhou; Meixia He; Chunyan Wang; Zhanzheng Zhao; Zhangsuo Liu Background: Diabetic nephropathy (DN) is a major cause of end-stage renal disease and proteinuria is one of the most prominent clinical manifestations. The expression of Vitamin D...
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Cellular Physiology and Biochemistry (2017) 42 (4): 1481–1492.
Published Online: 18 July 2017
...Sutong Li; Xiaoxia Liu; Jie Lei; Junle Yang; Puxun Tian; Yi Gao Background/Aims: Diabetic nephropathy (DN) is a microangiopathic disease characterized by excessive urinary albumin excretion, which occurs in 30% of patients with diabetes mellitus. It is the second leading cause of end-stage renal...
Journal Articles
Cellular Physiology and Biochemistry (2016) 39 (1): 183–192.
Published Online: 24 June 2016
...Qing Li; Ji Li; Hua Shao; Xiao-Xue Li; Feng Yu; Ming Xu Background/Aims: Our previous studies have indicated that a novel endothelin receptor antagonist CPU0213 effectively normalized renal function in diabetic nephropathy. However, the molecular mechanisms mediating the nephroprotective role...
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Cellular Physiology and Biochemistry (2016) 38 (6): 2479–2488.
Published Online: 17 June 2016
.... Diabetic nephropathy LC3II Autophagosome Renal fibrosis Diabetic nephropathy (DN), as one of the most serious complications of diabetes mellitus, is the main cause of end-stage renal failure (ESRD). However, effective treatment for reducing proteinuria and delaying progression of renal...
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