... to diabetes-associated colonic dysmotility. Methods: Control and streptozotocin (STZ)-induced diabetic groups were treated with aminoguanidine (AG). The colonic transit time and contractility of circular muscle strips was measured. ELISA, immunohistochemistry and western blotting were used to measure N ε...

... Colonic dysmotility Gastrointestinal (GI) dysfunction is very common in patients with diabetes, and the cause is multifactorial. Approximately 75% of patients with diabetes experience some form of GI dysfunction. The major complaints of those patients include dysphagia, reflux, early satiety...