...Yi Xu; Yue Yao; Kaiming Leng; Daolin Ji; Lijun Qu; Yueping Liu; Yunfu Cui Background/Aims: Circular RNAs (circRNAs) are a class of non-coding RNAs. They have been proved to be critically involved in tumorigenesis and progression of malignancies through competing endogenous RNA (ceRNA) mechanism...

...Guo-Hua Gong; Feng-Mao An; Yu Wang; Ming Bian; Di Wang; Cheng-Xi Wei Background/Aims: Temporal lobe epilepsy (TLE) is the most common form of adult localization-related epilepsy that is accompanied by progressive etiopathology and high incidences of drug resistance. Circular RNAs (circRNAs) play...

...-fibrogenic effects in HSCs through PI3K/AKT pathway. However, the underlying mechanisms are not fully elucidated. Circular RNAs (circRNAs) play important roles in fine-tuning gene expression and are often deregulated in cancers. However, the expression profile and clinical significance of in liver fibrosis...

... of the transcriptome of circular RNAs (circRNAs) in the brain tissues of rats with PWMD. Methods: We compared the expression profiles of circRNAs in brain samples from three rats with PWMD and three paired control tissues using deep RNA sequencing. Bioinformatics analysis was applied to investigate...

... to be elucidated. Circular RNAs (circRNAs), a novel class of endogenous non-coding RNAs, have recently been recognized as important regulators of gene expression and pathological processes. Here, we aimed to investigate the expression patterns of circRNAs after intestinal I/R with and without iPoC and, furthermore...

...Jiandong Shi; Ningzhu Hu; Ling Mo; Zhaoping Zeng; Jing Sun; Yunzhang Hu Background/Aims: Circular RNAs (circRNAs), a new class of regulators of gene expression, are involved in diverse physiological and pathogenic processes. However, their role in cellular responses to virus infection is yet...

...Hongli Chen; Tian Liu; Jing Liu; Yuandong Feng; Baiyan Wang; Jianli Wang; Ju Bai; Wanhong Zhao; Ying Shen; Xiaman Wang; Juan Yang; Yuqiang Ji; Aili He; Yun Yang Background/Aims: Circular RNAs (circRNAs) are a family of novel non-coding RNAs associated with various diseases, especially cancer...

..., instructions or products referred to in the content or advertisements. Laryngeal squamous cell carcinoma CD133+CD44+ Cancer stem cells Whole transcriptome analysis Circular RNA Laryngeal cancer is one of the most common malignant tumors worldwide; it affects approximately 10, 000 Americans...

...Xiu-Miao Li; Hui-Min Ge; Jin Yao; Yun-Fan Zhou; Mu-Di Yao; Chang Liu; Hai-Tao Hu; Yun-Xi Zhu; Kun Shan; Biao Yan; Qin Jiang Background/Aims: Pterygium is a common ocular surface disease with an unknown etiology and threatens vision as it invades into the cornea. Circular RNAs (circRNAs) are a novel...

.... Circular RNA (circRNA) is a novel type of noncoding RNA that can serve as an ideal biomarker due to its stability. Recent evidence suggests that circRNAs play important roles in tumorigenesis. This study aims to investigate circRNA expression profiles and their potential biological functions in PTC...

...Zhiqiang Chen; Long Zhang; Guoyong Han; Xueliang Zuo; Yao Zhang; Qin Zhu; Jindao Wu; Xuehao Wang Background/Aims: Circular RNAs (circRNAs), a novel class of noncoding RNAs, have been found to be dysregulated in various cancers. However, the clinical application value of these circRNAs in digestive...

...Bai-Hui Liu; Bin-Bin Zhang; Xiang-Qi Liu; Shan Zheng; Kui-Ran Dong; Rui Dong Background/Aims: Hepatoblastoma is the most common malignant pediatric liver cancer. circular RNAs (circRNAs) play important roles in fine-tuning gene expression and are often deregulated in cancers. However...

...Haimin Li; Xiaokun Hao; Huimin Wang; Zhengcai Liu; Yong He; Meng Pu; Hongtao Zhang; Hengchao Yu; Juanli Duan; Shibin Qu Background/Aims: Circular RNAs (circRNAs) are a special novel type of a stable, diverse and conserved noncoding RNA in mammalian cells. Particularly in cancer, circRNAs have been...