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Keywords: Cholinergic receptors
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Journal Articles
Effects of Nicotine on PTHrP and PTHrP Receptor Expression in Rat Coronary Endothelial Cells
Available to PurchaseSubject Area:
Further Areas
Anja Röthig, Rolf Schreckenberg, Kerstin Weber, Charlotte Conzelmann, Rui Manuel da Costa Rebelo, Klaus-Dieter Schlüter
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2012) 29 (3-4): 485–492.
Published Online: 03 April 2012
... of PTHrP release (≈8%). Antagonists directed against the α7 subunit of cholinergic receptors, the most prominent isoform, attenuated nicotine-dependent increases of PTHrP expression. This effect of nicotine was p38 MAPK dependent. Nicotine at micromolar concentrations reduced PTHrP receptor expression...
