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Keywords: Cellular Senescence
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Cellular Physiology and Biochemistry (2018) 51 (3): 1103–1118.
Published Online: 26 November 2018
...Maximilian Rentschler; Yan Chen; Jana Pahl; Laura Soria-Martinez; Heidi Braumüller; Ellen Brenner; Oliver Bischof; Martin Röcken; Thomas Wieder Background/Aims: Cellular senescence, or permanent growth arrest, is known as an effective tumor suppressor mechanism that can be induced by different...
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Cellular Physiology and Biochemistry (2017) 43 (4): 1369–1380.
Published Online: 09 October 2017
... was recorded by Cell Counting Kit-8. Effects of H7N9/NS1 on cellular senescence were investigated by senescence-associated β-galactosidase (SA-β-gal) staining, immunofluorescent staining of phosphorylated heterochromatin protein 1γ (pHP1γ) and qPCR analysis of IL-6 and IL-8. Results: H7N9/NS1 in Neuro2a cells...
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Cellular Physiology and Biochemistry (2016) 38 (1): 401–414.
Published Online: 29 January 2016
... with a significant increase in cellular senescence were detected in hUC-MSCs after exposure to indoxyl sulfate. Additionally, their ability to stimulate CD4 + CD25 + FoxP3 + regulatory T cell production was compromised when hUC-MSCs were pretreated with indoxyl sulfate. Conclusion: Taken together, our study clearly...
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Cellular Physiology and Biochemistry (2015) 36 (3): 1163–1174.
Published Online: 25 June 2015
... differentiation Cellular senescence Stem cells are characterized by their stemness: the capability of self-renewal and multipotential differentiation [ 1 ]. Liver progenitor cells (LPCs) are bipotent cells which can self-renew and differentiate into hepatocytes and biliary epithelial cells under specific...
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Cellular Physiology and Biochemistry (2015) 35 (3): 1151–1166.
Published Online: 06 February 2015
... studies have confirmed that Gas6 is involved in certain pathophysiological processes of the cardiovascular system through binding to its receptor, Axl. In the present study, we investigated the role of Gas6 in cellular senescence and explored the mechanisms underlying its activity. Methods: We used...
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