...Xin Jin; Hao Jin; Yan Shi; Yiyuan Guo; Hong Zhang Background/Aims: KCNQ1OT1 regulates the expression of tissue-specific imprinted genes within the Kcnq1 domain. Imprinted genes are positive regulators of apoptosis, one of the forms of cell death related to cataract formation, and thus may provide...

...Yinghong Ji; Xianfang Rong; Dan Li; Lei Cai; Jun Rao; Yi Lu Background/Aims: Ultraviolet B (UVB) irradiation can easily induce apoptosis in human lens epithelial cells (HLECs) and further lead to various eye diseases including cataract. Here for the first time, we investigated the role of cartilage...

...Qi Fan; Yonglong Zhang; Yanfeng Liu; Jin Yang; Dan Li; Yating Tang; Lei Cai; Zhennan Zhao; Peng Zhou; Yi Lu Background/Aims: Oxidative stress plays a critical role in the development of cataracts, and glutaredoxins (Grxs) play a major protective role against oxidative stress in the lens. This study...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Autophagy Age-related macular degeneration Glaucoma Cataract...