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Keywords: CFTR opener
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Journal Articles
Activation of the CFTR Cl - Channel by Trimethoxyflavone in vitro and in vivo
Available to PurchaseSubject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2008) 22 (5-6): 685–692.
Published Online: 09 December 2008
... the nasal mucosa activated nasal PD by -9.5±1.1 mV, which was 69% of the effect of TMF+isoproterenol (-13.8±3.9 mV). These data show that TMF is an activator of CFTR in both in vitro and in vivo assays that targets mainly the unstimulated CFTR. CFTR opener Flavonoid Electrophysiology Patch clamp...