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Keywords: CFTR mutants
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Cellular Physiology and Biochemistry (2017) 41 (6): 2194–2210.
Published Online: 25 April 2017
... recent advances in precision medicines for CF patients, many CFTR mutants have not been characterized and the effects of these new therapeutic approaches are still unclear for those mutants. Methods: Cells transfected or stably expressing four CFTR transmembrane-domain mutants (G85E, E92K, L1077P...