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1-5 of 5
Keywords: CDK4
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Journal Articles
Subject Area:
Further Areas
Xiangyu Zhu, Si-ping Ma, Dongxiang Yang, Yanlong Liu, Yong-peng Wang, Tao Lin, Yan-xi Li, Shi-hua Yang, Wan-chuan Zhang, Xin-ling Wang
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2018) 51 (4): 1969–1981.
Published Online: 04 December 2018
... capacity of CRC-derived cells and tumor cell growth in xenografted nude mice. In addition, we identified CDK4 as a potential target of miR-142-3p by predictions and dual-luciferase reporter assays. Concordantly, we found that miR-142-3p mimics and inhibitors could decrease and increase CDK4 protein levels...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2017) 42 (5): 2043–2065.
Published Online: 11 August 2017
... the expression of cyclin D1, CDK4 and p21 proteins. Conclusion: The cytotoxicity of P. spinosa oils were mediated by apoptosis and cell cycle arrest, suggesting the potential use of their bioactive compounds as natural anticancer compounds. salehay@ksau-hs.edu.sa 2 05 2017 20 06 2017 11 8...
Journal Articles
Subject Area:
Further Areas
Elisabeth Lang, Christine Zelenak, Matthias Eberhard, Rosi Bissinger, Anand Rotte, Mehrdad Ghashghaeinia, Adrian Lupescu, Florian Lang, Syed M. Qadri
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 37 (3): 1178–1186.
Published Online: 29 September 2015
...Elisabeth Lang; Christine Zelenak; Matthias Eberhard; Rosi Bissinger; Anand Rotte; Mehrdad Ghashghaeinia; Adrian Lupescu; Florian Lang; Syed M. Qadri Background/Aims: The cyclin-dependent kinase 4 (CDK4) participates in the regulation of apoptosis of nucleated cells by altering transcriptional...
Journal Articles
Subject Area:
Further Areas
Ayman M. Saleh, Ahmad Aljada, Mustafa M. El-Abadelah, Mutasem O. Taha, Salim S. Sabri, Jalal A. Zahra, Mohammad Azhar Aziz
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2015) 35 (5): 1943–1957.
Published Online: 27 March 2015
.../G1 phase in a dose and time-dependent manner. Furthermore, 5'-Cl treatment significantly inhibited expression of D-cyclins, CDK2 and CDK4 and suppressed phosphorylation of the retinoblastoma protein Rb, whereas it increased the level of CKI p21. Molecular modelling experiments show that 5'-Cl may...
Journal Articles
Subject Area:
Further Areas
Journal:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry (2014) 34 (4): 1351–1358.
Published Online: 02 October 2014
... respectively treated with various concentrations of formononetin. The inhibitory effect of formononetin on proliferation of prostate cancer cells was determined using MTT assays and flow cytometry. Next, formononetin-induced alterations in cyclin D1, CDK4 and Akt expression in PC-3 cells were detected by real...