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Keywords: Breast Cancer
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Cellular Physiology and Biochemistry (2018) 50 (1): 52–65.
Published Online: 16 October 2018
... to a poor prognosis and chemoresistance in breast cancer patients. Although Grb2-associated binding protein 2 (Gab2) is important in the development and progression of human cancer, its effects and mechanisms in HER2-overexpressing breast cancer are unclear. Methods: Clone formation and MTT assays were used...
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Cellular Physiology and Biochemistry (2018) 50 (2): 489–500.
Published Online: 11 October 2018
...Kholoud Arafat; Elham Al Kubaisy; Shahrazad Sulaiman; Sherif M. Karam; Zeina Al Natour; Ahmed H. Hassan; Samir Attoub Background/Aims: Breast cancer is the most common cancer in women worldwide, and within this cancer type, triple-negative breast cancers have the worst prognosis. The identification...
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Cellular Physiology and Biochemistry (2018) 50 (1): 136–149.
Published Online: 02 October 2018
...Jun Li; Mingjie Lu; Jiao Jin; Xiyi Lu; Tongpeng Xu; Shidai Jin Background/Aims: Most of estrogen receptor positive breast cancer patients respond well initially to endocrine therapies, but often develop resistance during treatment with selective estrogen receptor modulators (SERMs...
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Cellular Physiology and Biochemistry (2018) 48 (6): 2318–2336.
Published Online: 16 August 2018
...Shenglong Zhu; Ninghan Feng; Guangxiao Lin; Yuelin Tong; Xuan Jiang; Qin Yang; Shunhe Wang; Wei Chen; Zhao He; Yong Q Chen Background/Aims: Rapamycin (Rp), the main mammalian target of rapamycin complex inhibitor, is a promising therapeutic agent for breast cancer. However, metabolic disorders...
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Cellular Physiology and Biochemistry (2018) 48 (3): 1139–1150.
Published Online: 24 July 2018
... of these transcripts responsible for their dysregulation in breast cancer (BC) are not thoroughly understood. Methods: We examined the expression of microRNA miR-1471 in BC specimens. Online analysis tools predicted that lncRNA LOC101930370 might act as an endogenous ‘sponge’ by competing for miR-1471 binding targets...
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Cellular Physiology and Biochemistry (2018) 47 (6): 2569–2578.
Published Online: 11 July 2018
... breast cancer risk. The aim of this study was to investigate effects of single-nucleotide polymorphisms (SNPs) in FGFR1 on breast cancer susceptibility and FGFR1 protein expression. Methods: SNPs rs17182023, rs17175624 and rs10958704 in FGFR1 were genotyped in 747 breast cancer cases and 716 healthy...
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Cellular Physiology and Biochemistry (2018) 47 (5): 2126–2135.
Published Online: 05 July 2018
... is functionally linked to Jab1 in breast cancer. Methods: In situ hybridization and immunohistochemical analyses were used to determine the level of let-7d and Jab1 in breast cancer clinical specimens and its correlation with clinicopathological data. Let-7d overexpressing breast cancer cell lines combined...
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